Univariate analysis of predictors for pathologic complete response
| Characteristics | pCR | Partial response | No response | P |
|---|---|---|---|---|
| n = 12 (%) | n = 24 (%) | n = 28 (%) | ||
| Total (n=64) | 12 (19) | 24 (37) | 28 (44) | |
| Gender | ||||
| Female | 4 (14) | 12 (43) | 12 (43) | 0.632 |
| Male | 8 (22) | 12 (33) | 16 (45) | |
| Age, years | ||||
| <40 | 3 (21) | 6 (43) | 5 (36) | 0.783 |
| 40-69 | 6 (16) | 15 (40) | 16 (44) | |
| ≥70 | 3 (23) | 3 (23) | 7 (54) | |
| Distance from AV (cm) | ||||
| ≤5 | 6 (17) | 14 (39) | 16 (44) | 0.812 |
| 6-10 | 6 (21) | 10 (36) | 12 (43) | |
| Differenciation | ||||
| Well differentiated | 6 (100) | 0 | 0 | 0.001 |
| MD* | 6 (19) | 13 (42) | 12 (39) | |
| Undifferenciated | 0 | 11 (40) | 16 (60) | |
| Clinical T stage | ||||
| T2 | 6 (43) | 6 (43) | 2 (14) | 0.031 |
| T3 | 5 (13) | 14 (37) | 17 (45) | |
| T4 | 1 (8) | 4 (33) | 7 (58) | |
| Lymph node involvment | ||||
| N- | 7 (42) | 5(29) | 5 (29) | 0.021 |
| N + | 5 (11) | 19 (40) | 23 (49) | |
| Initial CEA (ng/mL) AC | ||||
| ≤5 | 12 (31) | 17 (48) | 9 (21) | 0.01 |
| >5 | 0 | 7 (27) | 19 (73) | |
| Radiological downstaging | ||||
| Yes | 1(4) | 4 (14)(55) | 23 (82)(14) | 0.001 |
| No | 11 (31) | 20 (55) | 5 (14) | |
| Interval from neoadjuvant treatment to operation (wk) | ||||
| ≤8 | 9 (16) | 21 (37) | 26 (47) | 0.294 |
| >8 | 3 (37) | 3 (37) | 2 (26) | |
| Neoadjuvant treatment | ||||
| RT | 4 (10) | 20 (50) | 16 (40) | 0.021 |
| CCRT | 8 (33) | 10 (42) | 6 (25) | |
| Initial Hb level (g/dL) | ||||
| <12 | 1 (8) | 5 (38) | 7 (54) | 0.009 |
| ≥12 | 7 (64) | 3(27) | 1 (9) | |
MD: moderately differentiated.