3

Multivariate analyses of factors associated with OS and TTR

VariableOSTTR
Hazard ratio (95% CI)PHazard ratio (95% CI)P
AFP (ng/mL; > 20 vs. ≤ 20)1.333 (0.785-2.265)0.035
ALT (U/L; > 75 vs. ≤ 75)1.960 (1.059-3.629)0.287
Tumor size (cm; > 5 vs. ≤ 5)1.687 (1.007-2.825)0.0471.667 (0.959-2.897)0.070
Tumor number (multiple vs. single)1.585 (0.557-4.506)0.388
Vascular invasion (yes vs. no)2.033 (1.230-3.359)0.0061.664 (0.991-2.792)0.054
Bcl-2 (high vs. low)0.458 (0.275-0.761)0.0030.391 (0.232-0.659)<0.001

95% CI, 95% confidence interval; AFP, alpha-fetoprotein; NS, not significant (Cox proportional hazards regression model).