5

Comparison of pathological features between SNP-positive and -negative at –402 of FVII promoter in HCC patients

Variable–402 SNP typeP
TotalGGNon-GG
Age (years)1.000
 ≥ 5025916
 < 501257
Sex0.700
 Male291118
 Female835
AFP (ng/mL)0.840
 < 2018711
 ≥ 2019712
Tumor size (cm)0.120
 ≥ 5 cm1486
 < 5 cm23617
Liver cirrhosis0.640
 Present18810
 Absent19613
Hepatitis0.930
 B23815
 C633
 B+C000
 NBNC835
TNM stage0.300
 I716
 II19910
 III945
Pathological features1.000
Capsule
 Present624
 Absent281216
Satellite nodule0.624
 Present523
 Absent301218
Microvascular invasion0.699
 Present251015
 Absent1046
Histological grade0.345
 I514
 II271314
 III101

SNP; single nucleotide polymorphism.