Genotype distributions of SNPs at the second exon of HLA-DRB1 in the study subjects.
| Genotype | Patients n = 30 (%) | Controls n = 66 (%) | P | χ2 | OR | 95%CI |
|---|---|---|---|---|---|---|
| rs17879702a | ||||||
| CC | 25 (83.3) | 43 (65.2) | 0.017 | 5.830 | 0.222 | [0.061-0.814] |
| CT | 3 (10.0) | 22 (33.3) | ||||
| TT | 2 (6.7) | 1 (1.5) | ||||
| rs17880292b | ||||||
| GG | 21 (70.0) | 58 (87.9) | 0.033 | 4.524 | 0.322 | [0.110-0.943] |
| GA | 9 (30.0) | 8 (12.1) | ||||
| AA | 0 | 0 | ||||
| rs1059586c | ||||||
| CC | 2 (6.7) | 6 (9.1) | 0.029 | 4.747 | 2.657 | [1.089-6.482] |
| CA | 9 (30.0) | 34 (51.5) | ||||
| AA | 19 (63.3) | 26 (39.4) | ||||
| rs17882525d | ||||||
| CC | 1 (3.3) | 1 (1.5) | 0.025 | 5.001 | 0.128 | [0.016-1.024] |
| CT | 1 (3.3) | 14 (21.2) | ||||
| TT | 28 (93.3) | 51 (77.3) | ||||
↵a. Association was analyzed by Fisher’s exact test. P-values and odds ratios for C/T+T/T genotype relative to C/C genotype.
↵b. Association was analyzed by Fisher’s exact test. P-values and odds ratio for G/A genotype relative to G/G genotype.
↵c. Association was analyzed by Fisher’s exact test. P-values and odds ratio for C/C+C/A genotype relative to A/A genotype.
↵d. Association was analyzed by Fisher’s exact test. P-values and odds ratio for C/C+C/T genotype relative to T/T genotype.