Table 1.

Relationship between TGF-β1, Snail, N-cadherin and E-cadherin expression and clinicopathologic factors.

	n	TGF-β1		Snail		N-cadherin		E-cadherin
Parameters	n	Positive	P^{^a}	Positive	P^{^a}	Positive	P^{^a}	Positive	P^{^a}
Differentiation			0.000		0.020		0.016		0.006
High	19	5		12		3		11
Middle	15	7		12		7		9
Poor	62	49		56		33		16
Histological Type^{^b}			0.000		0.000		0.000		0.000
Pap	10	2		3		1		6
Tub	24	11		20		12		15
Por	42	37		38		27		14
Sig/muc	20	11		19		3		1
Invasion depth			0.020		0.025		0.017		0.026
Above Serosa	16	6		10		3		10
Serosa	80	55		70		40		26
Lymph node metastasis			0.017		0.038		0.019		0.026
No	32	15		23		9		17
Yes	64	46		57		34		19
Pathologic stage			0.117		0.068		0.071		0.005
I~II	29	15		21		9		17
III~IV	67	46		59		34		19
Distant metastasis			0.045		0.049		0.016		0.038
No	86	52		70		35		35
Yes	10	9		10		8		1

↵a P was calcutated by χ² test.
↵b Japanese Gastric Cancer Association: Pap, papillary adenocarcinoma; Tub, tubular adenocarcinoma; Por, poorly differentiated adenocarcinoma; Sig, signet-ring cell carcinoma; Muc, mucinous adenocarcinoma.