Table 3.

Geometric means (95% confidence intervals) of mRNA levels for the the TGF-β1, TβR-I, and TβR-II genes in cancer and adjacent normal tissues from patients with breast cancer.

ItemTumor tissueAdjacent normal tissuePercent differenceap-valueb
TGF-β type II receptor (n=140)52.09
(45.00-60.30)		121.22
(103.31-142.22)		-57.0<0.001
TGF-β type I receptor (n=112)6.50
(5.81-7.26)		7.20
(6.48-7.99)		-9.70.055
TGF-β I (n=133)70.87
(63.68-78.86)		85.09
(75.68-95.67)		-16.70.142
TGF-β I / TβR-II (n=112)1.38
(1.19-1.61)		0.73
(0.62-0.87)		89.0<0.001
TGF-β I / TβR-I (n=98)10.90
(9.32-12.73)		10.73
(9.20-12.51)		1.60.853

  • ↵a Calculated by [(tumor tissue-adjacent normal tissue)/adjacent normal tissue]×100.

  • ↵b Derived from paired t-test.