Inhibitory effect of nimesulide on SGC-7901 cells (mean±SD, n=12)
| 24 h | 48 h | 72 h | ||||
|---|---|---|---|---|---|---|
| Cone μmol/L) | A value | JR | A value | IR | A value | IR |
| 0 | 0.973 ± 0.146 | 0.00 | 0.001.154 ± 0.158 | 0.00 | 1.242 ± 0.132 | 0.00 |
| 12.5 | 0.956 ± 0.111 | 1.72 | 1.119 ± 0.090 | 3.03 | 1.177 ± 0.089 | 5.30 |
| 50 | 0.882 ± 0.099 | 9.35 | 9.350.946 ± 0.081* | 18.02 | 0.944 ± 0.077* | 24.00 |
| 100 | 0.795 + 0.090* | 18.24 | 0.777 ± 0.083* | 32.64 | 0.686 ± 0.080* | 44.75 |
| 200 | 0.643 ± 0.081* | 33.94 | 0.574 ± 0.084* | 50.23 | 0.487 ± 0.071* | 60.83 |
| 400 | 0.473 + 0.101* | 51.34 | 0.402 ± 0.103* | 65.15 | 0.337 ± 0.041* | 72.89 |
| C-DDP (10 n-mol/L) | 0.321 ± 0.035* | 66.96 | 0.190 ± 0.052* | 83.52 | 0.080 ± 0.045* | 93.53 |