Likelihood ratios for the association between HER-2 status and no histologic response to chemotherapy.
| Studies | N (n) | Positive LR (95% CI) | Q | Negative LR (95% CI) | Q |
|---|---|---|---|---|---|
| All | 6 (247) | 1.27 (0.91-1.77) | 8.78 | 0.68 (0.38-1.22) | 11.13 |
| 1 | 4 (206) | 1.34 (0.92-1.95) | 7.83 | 0.56 (0.25-1.26) | 9.83 |
| 2 | 3 (125) | 1.62 (1.24-2.11) | 0.02 | 0.37 (0.20-0.68) | 0.23 |
All figures are based on random effects calculation. All P values for between-study heterogneity were > 0.05. Abbreviations: 1, studies scoring for membranous staining; 2, studies using the 25% IHC cutoff.