Table 1.

Cyctotoxicity of EBB on cell lines in vitroa

Cell linesIC50 (μmol/L)b
Wild type tumor cells
    PG (lung carcinoma)7.66 ± 2.31
    BE-1 (lung carcinoma)7.36 ± 1.26
    HL60 (myeloid leukemia)4.55 ± 1.74
    SKOV3 (ovarian carcinoma)9.83 ± 1.60
    M21 (melanoma)8.26 ± 0.18
    COC1 (ovarian carcinoma)6.58 ± 2.95
    KB (epidermoid carcinoma)13.86 ± 7.11
    MCF-7 (breast carcinoma)15.74 ± 2.21
Drug resistant tumor cells
    COC1/DDP (ovarian carcinoma)4.72 ± 0.81
    KBv200 (epidermoid carcinoma)9.03 ± 0.71
    MCF-7/ADR (breast carcinoma)14.67 ± 3.42

  • ↵a: Determined by MTT assays.

  • ↵b: Each number represents the mean±SD values of triplicate determinations in at least three separate experiments.