Differences among severe toxicities from chemotherapy between the 2 groups.
| Groups | Chemotherapy plus CIK | Chemotherapy alone | P value |
|---|---|---|---|
| Chemotherapy cycle | 239 | 217 | - |
| Leucopenia (grade 3 and 4) | 10 | 18 | 0.068 |
| Neutropenia (grade 3 and 4) | 17 | 22 | 0.249 |
| Diarrhea (grade 3 and 4) | 6 | 8 | 0.589 |
| Other grade 3 and 4 toxicities | 4 | 3 | 0.553 |
| Total grade 3 and 4 events | 37 | 51 | 0.030 |
| Patients with neutropenia fever | 1 | 6 | 0.088 |
| Patients unable to endure further chemotherapy due to toxicities | 4 | 12 | 0.045 |