Distribution of major risk factors in HCC patients with and without cirrhosis.
| Risk factor | HCC with cirrhosis (n=253) | HCC without cirrhosis (n=104) | |||||
|---|---|---|---|---|---|---|---|
| Cases positive | Healthy controls | OR (95%CI) | Cases positive | Healthy controls | OR(95%CI) | ||
| HBV status | |||||||
| Any marker+ | 176 (69.56) | 9 (7.5) | 28.19 (13.03-62.96) | 61(58.65) | 9 (7.5) | 17.50 (7.58-41.59) | |
| HBsAg+, antibody+ | 154 (60.86) | 8 (6.67) | 21.78 (9.77-50.50) | 54 (51.92) | 8 (6.67) | 15.12 (6.35-37.30) | |
| HbsAg-, antibody+ | 21 (8.30) | 1 (0.83) | 10.77 (1.51-217.67) | 6 (5.77) | 1 (0.83) | 7.29 (0.85-163.31) | |
| HCV status | |||||||
| Anti HCV+overall | 55 (21.74) | 3 (2.50) | 10.83 (3.17-44.39) | 3 (2.88) | 3 (2.50) | 1.16 (0.18-7.37) | |
| Anti HCV+, HCV RNA+ | 43 (17.00) | 2 (1.66) | 12.08 (2.80-73.44) | 3 (2.88) | 2 (1.66) | 1.75 (0.23-15.31) | |
| Anti HCV+, HCV RNA- | 12 (4.74) | 1 (0.83) | 5.93 (0.79-123.43) | 0 | 1 (0.83) | - | |
| Heavy alcohol Use | 1 (0.83) | 1 (0.83) | |||||
| + | 65 (25.69) | 13 (10.83) | 2.85 (1.44-5.70) | 14 (13.46) | 13 (10.83) | 1.28 (0.53-3.08) | |