Prevalence of viral infection and heavy alcohol use among HCC patients with and without cirrhosis.
| Etiological association | HCC with cirrhosis, n=253 (%) | HCC without cirrhosis, n=104 (%) | P |
|---|---|---|---|
| HBV marker | |||
| Overall | 176 (69.56) | 61 (58.65) | 0.02526 |
| HbsAg+ | 154 (60.86) | 54 (51.92) | 0.06129 |
| Only Anti HBe+ | 9 (3.56) | 2 (1.92) | 0.2266 |
| Only IgG Anti HBc+ | 12 (4.74) | 4 (3.85) | 0.3716 |
| HCV markers | |||
| Overall | 55 (21.74) | 3 (2.88) | 0.000000638 |
| Anti HCV+, HCV RNA+ | 43 (17.00) | 3 (2.88) | 0.00004147 |
| Anti HCV+, HCV RNA- | 12 (4.74) | 0 | |
| HBV and HCV | 24 (9.49) | 0 | |
| Overall | 65 (25.69) | 14 (13.46) | 0.004946 |
| Alcohol alone | 8 (3.16) | 9 (8.65) | 0.01940 |
| Alcohol and virus | 59 (23.32) | 6 (5.77) | 0.00001529 |
| Alcohol and HBV | 31 (12.25) | 4 (3.85) | 0.005667 |
| Alcohol and HBVand HCV | 9 (3.56) | 0 | |
| Alcohol and HCV | 16 (6.32) | 1 (0.96) | 0.01153 |
| Negative for HBV, HCV and alcohol | 37 (14.62) | 30 (28.85) | 0.001280 |