Table 1.

The expression of uPA, PAI-1 mRNA and protein in histologic differentiation of GC.

GroupnuPAmRNA (protein)aPAI-1 mRNA (protein)b
-±+Positive %-±+Positive %
I90 (0)5 (3)4 (6)44.4*(66.7)*0 (0)4 (2)5 (7)54.6*(77.8)*
II395 (3)13 (13)21 (23)53.8 (60.0)3 (1)13 (12)23 (26)60.0 (66.7)
III6215 (10)10 (7)37 (45)59.7 (72.6)16 (13)13 (9)33 (40)53.2 (64.5)
  • Comparison among the groups of GC

  • ↵* P<0.05

  • ↵a The relationship between the expressions of uPA mRNA and protein was significantly positive, r =0.686, P < 0.001

  • ↵b The relationship between the expressions of PAI-1 mRNA and protein was significantly positive, r = 0.812, P < 0.001.