Relationship between the expression of uPA, PAI-1, MVD and clinicopathological parameters in GC.
| Parameters | n | MVD | uPA positive | PAI-1 positive | ||
|---|---|---|---|---|---|---|
| mRNA (%) | Protein (%) | mRNA (%) | Protein (%) | |||
| Clinical stage | ||||||
| I-II | 21 | 22.9 ± 3.1* | 7 (33.3) | 9 (42.9)* | 7 (33.3) | 14 (66.7) |
| III-IV | 89 | 26.2 ± 4.2 | 55 (61.8) | 65 (73.1) | 57 (64.0) | 59 (66.3) |
| Lymph node metastasis | ||||||
| Absent | 37 | 24.9 ± 3.8 | 16 (43.2) | 23 (62.2) | 16 (43.2) | 26 (70.3) |
| Present | 73 | 25.9 ± 4.4 | 46 (63.0) | 51 (69.9) | 48 (65.8) | 47 (64.4) |
↵* P < 0.05.