List of clinical chemotherapeutic drugs inducing autophagy in cancer cells
| Drug (generic name) | Trade name | Drug type | Cancer | Reference |
|---|---|---|---|---|
| 5-Fluorouracil | Adrucil | Antimetabolite | CRC | 83,223–225 |
| HCC | 82 | |||
| Asparaginase | Elspar/Kidrolase | Enzyme | ALL | 226 |
| Cisplatin | Platinol | Alkylating agent | Ovarian cancer | 227 |
| Esophageal cancer | 228 | |||
| Desmoid tumors | 229 | |||
| NSCLC | 230 | |||
| HGSOC | 231 | |||
| Dexamethasone | Decadron | Glucocorticosteroid | Lymphoid malignancy | 232 |
| Docetaxel | Taxotere | Plant alkaloid/taxane/antimicrotubule agent | Prostate cancer | 233 |
| Doxorubicin | Adriamycin/Rubex | Anthracycline antibiotic | Leukemia | 234 |
| Multiple myeloma | 235 | |||
| Melanoma | 236 | |||
| CRPC | 237 | |||
| Enzalutamide | Xtandi | Anti-androgen | Prostate cancer | 238 |
| Epirubicin | Ellence | Anthracycline antibiotic | TNBC | 239 |
| Breast cancer | 240 | |||
| HCC | 241 | |||
| Etoposide | Etopophos | Anthracycline antibiotic | SCLC | 242 |
| Gemcitabine | Gemzar | Antimetabolite | Pancreatic cancer | 243 |
| Irinotecan (CPT-11) | Camptosar | Plant alkaloid/topoisomerase I inhibitor | CRC | 244 |
| Oxaliplatin | Eloxatin | Alkylating agent | CRC | 30,245 |
| HCC | 82 | |||
| Paclitaxel | Taxol/Onxal | Plant alkaloid/taxane/antimicrotubule agent | Cervical cancer | 246 |
| Ovarian cancer | 247 | |||
| Breast cancer | 248 | |||
| Pemetrexed | Alimta | Antimetabolite | HCC | 249 |
| Vincristine | Oncovin | Plant alkaloid | Leukemia | 234 |
CRC, colorectal cancer; HCC, hepatocellular carcinoma; ALL, acute lymphocytic leukemia; NSCLC, non-small cell lung cancer; CRPC, castration-resistant prostate cancer; TNBC, triple negative breast cancer; SCLC, small cell lung cancer.