Prevalence of methylation of different genes in tissues of gliomas patients and relation to clinical data (%).
| Characteristics | Subject | MGMT | hMLH1 | hMSH2 | Any gene |
|---|---|---|---|---|---|
| Gender | |||||
| Male | 18 | 9 (50) | 2 (11.1) | 4 (22.2) | 12 (66.7) |
| Female | 21 | 9 (42.9) | 2 (9.5) | 4 (19) | 13 (61.9) |
| Age, years | |||||
| Mean age | 40.6 | 43.2 | 42.7 | 45.9 | 43.8 |
| Pathological type | |||||
| Astrocytoma | 11 | 6 (54.5) | 1 (9.1) | 2 (18.2) | 8 (72.7) |
| Oligodendroglioma | 5 | 1 (20) | 1 (20) | 2 (40) | |
| Oligoastrocytoma | 10 | 4 (40) | 1 (10) | 1 (10) | 5 (50) |
| Multiform-spongioblastoma | 13 | 7 (53.8) | 2 (15.4) | 4 (30.7) | 10 (76.9) |
| Stage | |||||
| Early | 17 | 7 (41.2) | 2 (11.8) | 3 (17.6) | 11 (64.7) |
| Late | 22 | 11 (50) | 2 (9.5) | 5 (22.7) | 14 (63.6) |
| Grade | |||||
| I~II | 15 | 7 (46.7) | 2 (13.3) | 2 (13.3) | 9 (60) |
| III~IV | 24 | 11 (45.8) | 2 (8.3) | 4 (16.7) | 16 (66.7) |