Table 1

Adverse events

No. (%) of patients in the I-CRT group (n = 98)No. (%) of patients in the CRT group (n = 284)
All gradesGrade ≥3All gradesGrade ≥3
Any adverse event of any cause95 (96.9)63 (64.3)280 (98.6)168 (59.2)
Nausea/vomiting46 (46.9)2 (2.0)190 (66.9)2 (0.7)
Leucopenia86 (87.8)29 (29.6)259 (91.2)87 (30.6)
Neutropenia78 (79.6)57 (58.2)256 (90.1)144 (50.7)
Thrombocytopenia29 (29.6)8 (8.2)87 (30.6)17 (6.0)
Rash9 (9.2)018 (6.3)0
Elevated ALT/AST30 (30.6)0102 (35.9)1 (0.4)
Esophagitis42 (42.9)1 (1.0)138 (48.6)0
Pneumonia47 (48.0)10 (10.2)112 (39.4)16 (5.6)