Table 3

Multivariate analysis of associations of patient, tumor, treatment, and pathologic characteristics with survival

Variable	Time to failure survival			Overall survival
Variable	HR	95% CI	P value	HR	95% CI	P value
TNM stage	1.393	0.59–3.289	0.449	0.125	0.006–2.384	0.350
IORT dose ≤ 15 (vs. > 15)	0.389	0.139–2.157	0.547	2.120	0.473–9.509	0.326
D-dimer < 500 (vs. ≥ 500)	0.219	0.070–0.682	0.009*	0.230	0.070–0.763	0.016*
CEA < 5 (vs. ≥ 5)	0.384	0.159–0.928	0.034*	0.281	0.109–0.725	0.009*
CA19-9 < 37 (vs. ≥ 37)	0.666	0.282–1.569	0.352	0.234	0.079–0.692	0.009*

↵*P < 0.05 was considered statistically significant. HR, hazard ratio; CI, confidence interval.