RT Journal Article SR Electronic T1 Work-up and management of a high-risk patient with primary central nervous system lymphoma JF Cancer Biology and Medicine JO Cancer Biol Med FD China Anti-Cancer Association SP 514 OP 518 DO 10.20892/j.issn.2095-3941.2016.0070 VO 13 IS 4 A1 Zeynalova, Pervin A. A1 Tumyan, Gayane S. A1 Dolgushin, Mikhail B. A1 Akhmedov, Mobil I. YR 2016 UL http://www.cancerbiomed.org/content/13/4/514.abstract AB Primary central nervous system lymphoma (PCNSL) is a rare disorder that, in 95% of cases, represents diffuse large B-cell lymphoma. As such, making an accurate diagnosis is important. At present, stereotactic-guided biopsy is a recognized method of choice for tissue analysis. However, the diagnostic work-up for high-risk patients is determined by their performance status. Here, we report a case of PCNSL in a high-risk patient, for whom diagnosis was established by cerebrospinal fluid cytology and flow cytometry, which significantly shortened a diagnostic work-up period and allowed for the immediate treatment of the patient.