PT - JOURNAL ARTICLE AU - Zeynalova, Pervin A. AU - Tumyan, Gayane S. AU - Dolgushin, Mikhail B. AU - Akhmedov, Mobil I. TI - Work-up and management of a high-risk patient with primary central nervous system lymphoma AID - 10.20892/j.issn.2095-3941.2016.0070 DP - 2016 Dec 01 TA - Cancer Biology and Medicine PG - 514--518 VI - 13 IP - 4 4099 - http://www.cancerbiomed.org/content/13/4/514.short 4100 - http://www.cancerbiomed.org/content/13/4/514.full SO - Cancer Biol Med2016 Dec 01; 13 AB - Primary central nervous system lymphoma (PCNSL) is a rare disorder that, in 95% of cases, represents diffuse large B-cell lymphoma. As such, making an accurate diagnosis is important. At present, stereotactic-guided biopsy is a recognized method of choice for tissue analysis. However, the diagnostic work-up for high-risk patients is determined by their performance status. Here, we report a case of PCNSL in a high-risk patient, for whom diagnosis was established by cerebrospinal fluid cytology and flow cytometry, which significantly shortened a diagnostic work-up period and allowed for the immediate treatment of the patient.