RT Journal Article
SR Electronic
T1 Recent advances of sonodynamic therapy in cancer treatment
JF Cancer Biology and Medicine
JO Cancer Biol Med
FD China Anti-Cancer Association
SP 325
OP 338
DO 10.20892/j.issn.2095-3941.2016.0068
VO 13
IS 3
A1 Guo-Yun Wan
A1 Yang Liu
A1 Bo-Wei Chen
A1 Yuan-Yuan Liu
A1 Yin-Song Wang
A1 Ning Zhang
YR 2016
UL http://www.cancerbiomed.org/content/13/3/325.abstract
AB Sonodynamic therapy (SDT) is an emerging approach that involves a combination of low-intensity ultrasound and specialized chemical agents known as sonosensitizers. Ultrasound can penetrate deeply into tissues and can be focused into a small region of a tumor to activate a sonosensitizer which offers the possibility of non-invasively eradicating solid tumors in a site-directed manner. In this article, we critically reviewed the currently accepted mechanisms of sonodynamic action and summarized the classification of sonosensitizers. At the same time, the breath of evidence from SDT-based studies suggests that SDT is promising for cancer treatment.