RT Journal Article
SR Electronic
T1 The role of radiotherapy in the management of localized soft tissue sarcomas
JF Cancer Biology and Medicine
JO Cancer Biol Med
FD China Anti-Cancer Association
SP 373
OP 383
DO 10.20892/j.issn.2095-3941.2016.0028
VO 13
IS 3
A1 Tiong, Siaw Sze
A1 Dickie, Colleen
A1 Haas, Rick L.
A1 O’Sullivan, Brian
YR 2016
UL http://www.cancerbiomed.org/content/13/3/373.abstract
AB The combination of radiotherapy (RT) and function-preserving surgery is the most usual contemporary approach in the management of soft tissue sarcomas (STS). Pre- and postoperative RT result in similar local control rates, as shown by a landmark trial in extremity STS. In this review, the role of RT in the management of extremity STS will be discussed, but STS in other sites, including retroperitoneal STS, will also be addressed. The focus will consider various aspects of RT including strategies to reduce the volume of tissue being irradiated, dose, scheduling, and the possible of omission of RT in selected cases. Finally, technology advances through the use of intensity-modulated radiotherapy (IMRT), image-guided IMRT, intraoperative radiotherapy (IORT) and particle therapy will also be discussed.