RT Journal Article
SR Electronic
T1 Current practices and guidelines for clinical next-generation sequencing oncology testing
JF Cancer Biology and Medicine
JO Cancer Biol Med
FD China Anti-Cancer Association
SP 3
OP 11
DO 10.28092/j.issn.2095-3941.2016.0004
VO 13
IS 1
A1 Strom, Samuel P.
YR 2016
UL http://www.cancerbiomed.org/content/13/1/3.abstract
AB Next-generation sequencing (NGS) has been rapidly integrated into molecular pathology, dramatically increasing the breadth genomic of information available to oncologists and their patients. This review will explore the ways in which this new technology is currently applied to bolster care for patients with solid tumors and hematological malignancies, focusing on practices and guidelines for assessing the technical validity and clinical utility of DNA variants identified during clinical NGS oncology testing.