PT - JOURNAL ARTICLE AU - Strom, Samuel P. TI - Current practices and guidelines for clinical next-generation sequencing oncology testing AID - 10.28092/j.issn.2095-3941.2016.0004 DP - 2016 Mar 01 TA - Cancer Biology and Medicine PG - 3--11 VI - 13 IP - 1 4099 - http://www.cancerbiomed.org/content/13/1/3.short 4100 - http://www.cancerbiomed.org/content/13/1/3.full SO - Cancer Biol Med2016 Mar 01; 13 AB - Next-generation sequencing (NGS) has been rapidly integrated into molecular pathology, dramatically increasing the breadth genomic of information available to oncologists and their patients. This review will explore the ways in which this new technology is currently applied to bolster care for patients with solid tumors and hematological malignancies, focusing on practices and guidelines for assessing the technical validity and clinical utility of DNA variants identified during clinical NGS oncology testing.