PT  - JOURNAL ARTICLE
AU  - WANG, Kai
AU  - WEI, Jin
TI  - Multi-Targeted Therapies in Non-Small Cell Lung Cancer
AID  - 10.1007/s11805-011-0584-6
DP  - 2011 Dec 01
TA  - Clinical Oncology and Cancer Research
PG  - 220--223
VI  - 8
IP  - 4
4099  - http://www.cancerbiomed.org/content/8/4/220.short
4100  - http://www.cancerbiomed.org/content/8/4/220.full
SO  - Cancer Biol Med2011 Dec 01; 8
AB  - Current treatment modalities provide limited improvement in the natural course of lung cancer, and prognosis remains poor. Lung cancer is a malignancy with great molecular heterogeneity. The complexity of the signaling process leading to cancer cell proliferation and to the neoplastic phenotype supports the necessity of interfering at different stages to avoid cancer cell resistance to therapy. For this reason, new strategies for the simultaneous inhibition of multiple molecular targets are being pursued.