RT Journal Article
SR Electronic
T1 Clinicopathological Analysis as Predictive Factors for Recurrence in Early Gastric Cancer
JF Chinese Journal of Clinical Oncology
JO Cancer Biol Med
FD China Anti-Cancer Association
SP 122
OP 124
DO 10.1007/s11805-008-0122-3
VO 5
IS 2
A1 Li, Hua
A1 Lu, Ping
A1 Liu, Caigang
A1 Xu, Huimian
A1 Wang, Shubao
A1 Chen, Junqing
YR 2008
UL http://www.cancerbiomed.org/content/5/2/122.abstract
AB OBJECTIVE To identify clinicopathological characteristics as predictive factors for recurrence in early gastric cancer (EGC), and to determine which lesions should be removed by gastrectomy by means other than endoscopic mucosal resection (EMR).METHODS Data from 249 patients with EGC were collected and the relationship between their clinicopathological characteristics and postoperative recurrence was retrospectively analyzed by univariate analysis.RESULTS Of the 249 patients after gastrectomy, 19 cases (7.6%) experienced a recurrence. The postoperative recurrence rate was 18.9% (7/37) in patients with lymph node metastasis, and 5.7% (12/212) in those without. Lymph node metastases were found to be significantly related to recurrence in EGC (P = 0.005).CONCLUSION Lymph node metastases were the only predictive factor for recurrence in EGC. However, this was not the determining factor for performing gastrectomy rather than EMR. Although after gastrectomy with lymphadenectomy of EGC, patients with lymph node metastasis should be considered as candidates for adjuvant treatment. For lymph-node metastatic EGCs, adjuvant therapy is recommended following gastrectomy with lymphadenectomy.