RT Journal Article SR Electronic T1 Transrectal Ultrasound-guided Systematic 13-Core Prostate Biopsy to Diagnose Prostate Carcinoma JF Chinese Journal of Clinical Oncology JO Cancer Biol Med FD China Anti-Cancer Association SP 849 OP 851 VO 2 IS 6 A1 Liuping Yang A1 Junhong Deng A1 Hong Zhong A1 Jianbo Hu A1 Hongai Wei A1 Liangsheng Wang YR 2005 UL http://www.cancerbiomed.org/content/2/6/849.abstract AB OBJECTIVE To evaluate the clinical value of transrectai ultrasound guided systematic 13-core prostate biopsy.METHODS A total of 213 patients referred for abnormal digital rectal examination and/or with a prostate specific antigen of 4 ng/ml or greater underwent transrectal ultrasound guided systematic 13-core prostate biopsy. This procedure was conducted in addition to the standard sextant biopsies in which cores were taken from the far lateral and middle regions of the gland as described by Eskew. Pathological findings of the additional regions were compared with those of the sextant regions.RESULTS Of the 213 patients 31% had cancer on biopsy (66/213). Of the 66 patients with prostate cancer 14 (21%) had carcinoma only in the additional regions, which would have remained undetected had the sextant biopsy technique been used alone (P<0.05). No severe complications occurred among the patients who underwent transrectal ultrasound guided systematic 13-core prostate biopsy.CONCLUSION Our data demonstrated that transrectal ultrasound guided systematic 13-core prostate biopsy can significantly increase the cancer detection rate. It is safe and efficacious, and should be recommended for use clinically.