PT  - JOURNAL ARTICLE
AU  - Liuping Yang
AU  - Junhong Deng
AU  - Hong Zhong
AU  - Jianbo Hu
AU  - Hongai Wei
AU  - Liangsheng Wang
TI  - Transrectal Ultrasound-guided Systematic 13-Core Prostate Biopsy to Diagnose Prostate Carcinoma
DP  - 2005 Dec 01
TA  - Chinese Journal of Clinical Oncology
PG  - 849--851
VI  - 2
IP  - 6
4099  - http://www.cancerbiomed.org/content/2/6/849.short
4100  - http://www.cancerbiomed.org/content/2/6/849.full
SO  - Cancer Biol Med2005 Dec 01; 2
AB  - OBJECTIVE To evaluate the clinical value of transrectai ultrasound guided systematic 13-core prostate biopsy.METHODS A total of 213 patients referred for abnormal digital rectal examination and/or with a prostate specific antigen of 4 ng/ml or greater underwent transrectal ultrasound guided systematic 13-core prostate biopsy. This procedure was conducted in addition to the standard sextant biopsies in which cores were taken from the far lateral and middle regions of the gland as described by Eskew. Pathological findings of the additional regions were compared with those of the sextant regions.RESULTS Of the 213 patients 31% had cancer on biopsy (66/213). Of the 66 patients with prostate cancer 14 (21%) had carcinoma only in the additional regions, which would have remained undetected had the sextant biopsy technique been used alone (P<0.05). No severe complications occurred among the patients who underwent transrectal ultrasound guided systematic 13-core prostate biopsy.CONCLUSION Our data demonstrated that transrectal ultrasound guided systematic 13-core prostate biopsy can significantly increase the cancer detection rate. It is safe and efficacious, and should be recommended for use clinically.