RT Journal Article
SR Electronic
T1 MRI Manifestions Correlate with Survival of Glioblastoma Multiforme Patients
JF Cancer Biology and Medicine
JO Cancer Biol Med
FD China Anti-Cancer Association
SP 120
OP 123
DO 10.3969/j.issn.2095-3941.2012.02.007
VO 9
IS 2
A1 Wen-bin Li
A1 Kai Tang
A1 Qian Chen
A1 Shuai Li
A1 Xiao-guang Qiu
A1 Shao-wu Li
A1 Tao Jiang
YR 2012
UL http://www.cancerbiomed.org/content/9/2/120.abstract
AB Objective To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM).Methods The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves.Results Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity.Conclusions Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.