PT  - JOURNAL ARTICLE
AU  - Feng, Gang
AU  - Zhao, Zhongquan
AU  - Wang, Dongiin
TI  - The Investigation of EWS-FLI-1 Fusion Gene in the Ewing Family of Tumors
DP  - 2004 Jun 01
TA  - Chinese Journal of Clinical Oncology
PG  - 225--228
VI  - 1
IP  - 3
4099  - http://www.cancerbiomed.org/content/1/3/225.short
4100  - http://www.cancerbiomed.org/content/1/3/225.full
SO  - Cancer Biol Med2004 Jun 01; 1
AB  - There is evidence that 95% of the Ewing family of tumors (EFT) have a EWS-FLI-1 fusion gene. EWS-FLI-1 is a transcription factor with a pivotal function and it is known to bind to a special DNA sequence. Research has demonstrated that the EWS-FLI-1 fusion gene occurrence is related to the EFT, and it has been used to diagnose, treat and serve as a basis for EFT prognosis. We have briefly summarized the progress of the EWS-FLI-1 fusion gene in basic and clinical investigation within the past several years.