RT Journal Article SR Electronic T1 Evaluation of an intelligent digital platform for population management in cervical cancer screening JF Cancer Biology & Medicine JO Cancer Biology & Medicine FD China Anti-Cancer Association SP 1068 OP 1082 DO 10.20892/j.issn.2095-3941.2025.0419 VO 22 IS 9 A1 Jia, Xinhua A1 Gao, Chen A1 Da, Xi’ao A1 Shi, Jingyi A1 Chen, Mingyang A1 Duan, Rufei A1 Li, Zhifang A1 Feng, Ruimei A1 Yang, Yao A1 Zhai, Jiahuan A1 Ding, Hanyue A1 Ng, Alex A1 Qiao, Youlin YR 2025 UL http://www.cancerbiomed.org/content/22/9/1068.abstract AB Objective: To describe temporal changes associated with deployment of an optical character recognition (OCR)-enabled One-Identity (One-ID) digital platform for rural cervical cancer screening, focusing on over-screening rates, CIN2+ detection, colposcopy follow-up, and CIN2+ management.Methods: A multi-county pre-post observational study was conducted in six rural counties in Shanxi, Yunnan, and Sichuan Provinces (2021–2024), encompassing 153,978 encounters. The digital platform integrates OCR identity capture, deterministic One-ID linkage, and real-time duplicate alerts. Over-screening proportions before and after digital deployment were compared, changes in CIN2+ detection rate were evaluated, and colposcopy follow-up and CIN2+ management were assessed. Differences were tested with χ2 or Fisher’s exact tests.Results: Among 153,978 encounters, the proportion of over-screening decreased from 12.64% in 2023 to 0.17% in 2024 with an absolute reduction of 12.17% (95% CI: 11.94–12.40; P < 0.001). The share of women receiving a first screening within the preceding 3 y increased from 78.3% to 88.2% (P < 0.001). Colposcopy completion improved from 64.1% to 84.9%. The CIN2+ detection rate rose from 0.35% (2021–2023 pooled) to 0.67% in 2024 (P < 0.001) and CIN2+ management completion increased from 56.0% to 76.2% (95% CI: 13.3–27.2; P < 0.001). These improvements were consistent across age groups, counties, and screening strategies.Conclusions: The OCR-enabled One-ID platform substantially reduced over-screening, increased CIN2+ detection rate, and strengthened case follow-up/management, particularly where baseline tracking was weak, supporting scalable digital reinforcement of rural screening programmes.The data underlying this article cannot be shared publicly due to the privacy of individuals that participated in the study.