Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
M Castellarin, RL Warren, JD Freeman… - Genome …, 2012 - genome.cshlp.org
An estimated 15% or more of the cancer burden worldwide is attributable to known
infectious agents. We screened colorectal carcinoma and matched normal tissue specimens …
infectious agents. We screened colorectal carcinoma and matched normal tissue specimens …
[HTML][HTML] Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System
Fusobacterium nucleatum is a common oral bacterium that is enriched in colorectal
adenomas and adenocarcinomas (CRC). In humans, high fusobacterial CRC abundance is …
adenomas and adenocarcinomas (CRC). In humans, high fusobacterial CRC abundance is …
Fusobacterium in Colonic Flora and Molecular Features of Colorectal Carcinoma
T Tahara, E Yamamoto, H Suzuki, R Maruyama… - Cancer research, 2014 - AACR
Fusobacterium species are part of the gut microbiome in humans. Recent studies have
identified overrepresentation of Fusobacterium in colorectal cancer tissues, but it is not yet …
identified overrepresentation of Fusobacterium in colorectal cancer tissues, but it is not yet …
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
The tumor microenvironment of colorectal carcinoma is a complex community of genomically
altered cancer cells, nonneoplastic cells, and a diverse collection of microorganisms. Each …
altered cancer cells, nonneoplastic cells, and a diverse collection of microorganisms. Each …
Fusobacterium nucleatum — symbiont, opportunist and oncobacterium
CA Brennan, WS Garrett - Nature Reviews Microbiology, 2019 - nature.com
Fusobacterium nucleatum has long been found to cause opportunistic infections and has
recently been implicated in colorectal cancer; however, it is a common member of the oral …
recently been implicated in colorectal cancer; however, it is a common member of the oral …
Southern Chinese populations harbour non-nucleatum Fusobacteria possessing homologues of the colorectal cancer-associated FadA virulence factor
Objective Fusobacteria are not common nor relatively abundant in non-colorectal cancer
(CRC) populations, however, we identified multiple Fusobacterium taxa nearly absent in …
(CRC) populations, however, we identified multiple Fusobacterium taxa nearly absent in …
[HTML][HTML] Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment
Increasing evidence links the gut microbiota with colorectal cancer. Metagenomic analyses
indicate that symbiotic Fusobacterium spp. are associated with human colorectal carcinoma …
indicate that symbiotic Fusobacterium spp. are associated with human colorectal carcinoma …
Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis
K Yamamura, Y Baba, S Nakagawa, K Mima… - Clinical Cancer …, 2016 - AACR
Purpose: Fusobacterium nucleatum (F. nucleatum) is a component of the human
microbiome that primarily inhabits the oral cavity. It causes periodontal disease and has also …
microbiome that primarily inhabits the oral cavity. It causes periodontal disease and has also …
Comparative analysis of colon cancer-derived fusobacterium nucleatum subspecies: inflammation and colon tumorigenesis in murine models
Fusobacteria are commonly associated with human colorectal cancer (CRC), but
investigations are hampered by the absence of a stably colonized murine model. Further …
investigations are hampered by the absence of a stably colonized murine model. Further …
RNA landscape of the emerging cancer-associated microbe Fusobacterium nucleatum
Fusobacterium nucleatum, long known as a constituent of the oral microflora, has recently
garnered renewed attention for its association with several different human cancers. The …
garnered renewed attention for its association with several different human cancers. The …
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