[HTML][HTML] Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

[HTML][HTML] Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

D Nejman, I Livyatan, G Fuks, N Gavert, Y Zwang… - Science, 2020 - science.org
Bacteria were first detected in human tumors more than 100 years ago, but the
characterization of the tumor microbiome has remained challenging because of its low …

[HTML][HTML] Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

JL Galeano Niño, H Wu, KD LaCourse… - Nature, 2022 - nature.com
The tumour-associated microbiota is an intrinsic component of the tumour microenvironment
across human cancer types,. Intratumoral host–microbiota studies have so far largely relied …

Human gut microbiota/microbiome in health and diseases: a review

EZ Gomaa - Antonie Van Leeuwenhoek, 2020 - Springer
The human gut microbiota has received considerable interest in the recent years and our
knowledge of the inhabitant species and their potential applications is increased particularly …

[HTML][HTML] What is the healthy gut microbiota composition? A changing ecosystem across age, environment, diet, and diseases

E Rinninella, P Raoul, M Cintoni, F Franceschi… - Microorganisms, 2019 - mdpi.com
Each individual is provided with a unique gut microbiota profile that plays many specific
functions in host nutrient metabolism, maintenance of structural integrity of the gut mucosal …

Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis

F Cao, L Jin, Y Gao, Y Ding, H Wen, Z Qian… - Nature …, 2023 - nature.com
Inflammatory bowel disease can be caused by the dysfunction of the intestinal mucosal
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …

[PDF][PDF] Fusobacterium nucleatum promotes chemoresistance to colorectal cancer by modulating autophagy

TC Yu, F Guo, Y Yu, T Sun, D Ma, J Han, Y Qian… - Cell, 2017 - cell.com
Gut microbiota are linked to chronic inflammation and carcinogenesis. Chemotherapy failure
is the major cause of recurrence and poor prognosis in colorectal cancer patients. Here, we …

[HTML][HTML] Role of the microbiota in immunity and inflammation

Y Belkaid, TW Hand - Cell, 2014 - cell.com
The microbiota plays a fundamental role on the induction, training, and function of the host
immune system. In return, the immune system has largely evolved as a means to maintain …

[HTML][HTML] The cancer genome atlas pan-cancer analysis project

JN Weinstein, EA Collisson, GB Mills, KR Shaw… - Nature …, 2013 - nature.com
Abstract The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed
large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein …