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Gut microecology empowers cancer immunotherapy: commensal microbiota-mediated mechanisms and translational prospects of PD-1/PD-L1 therapy
Sifan Li, Chang Che, Yelu Zhou, Daiming Fan, Xue Bai, Yuanyuan Lu and Xiaodi Zhao

Cancer Biology & Medicine January 2026, 20250347; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0347
Open Access
Rethinking anti-cancer drug discovery: the evolution from polypharmacy to unified drug units
Jun He and Xinbing Sui

Cancer Biology & Medicine January 2026, 20250641; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0641
Open Access
SPRED2 suppresses the stemness of hepatocellular carcinoma through the p53/miR-506-3p/KLF4 pathway
Tong Gao, Sachio Ito, Aye Moh-Moh-Aung, Tianyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Teizo Yoshimura and Akihiro Matsukawa

Cancer Biology & Medicine January 2026, 20250247; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0247
Open Access
Innovative cross-intervention: copper ions and metabolic pathways in cancer therapy
Lili Niu, Wei Su, Lixia Ju, Jun Xiang, Zhou Yang and Bing Yao

Cancer Biology & Medicine January 2026, 20250198; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0198
Open Access
Migration and invasion inhibitory protein inhibits M2 macrophage polarization to suppress colorectal cancer progression through the STING–NFκB2–IL10 axis
Shuai Chen, Chenglu Lu, Jiaxin Li, Xilin Shen and Yan Sun

Cancer Biology & Medicine January 2026, 20250282; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0282
Open Access
Temporal radiomics for non-invasive preoperative prediction of pathologic complete response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
Sunyi Zheng, Shuo Wang, Ziwei Feng, Jing Liang, Jiaxin Liu, Xiaomeng Yang, Zhanshuo Zhang, Yuechen Cui, Jiping Xie, Shuxuan Fan, Jing Wang, Guoqing Liao, Haiyu Zhou, Zhaoxiang Ye, Jianyu Xiao, Lei Shi, Xiaonan Cui and Dongsheng Yue

Cancer Biology & Medicine January 2026, 20250327; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0327
Open Access
Multi-cancer early detection: from promise to practice and the next frontier
Yongjie Xu and Wanqing Chen

Cancer Biology & Medicine December 2025, 20250664; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0664
Open Access
Impact of pre-neoadjuvant radioactive iodine seed marking on pathologic complete response and survival in early-stage breast cancer patients
Yihao Geng, Qi Zhang, Zhao Bi, Zhiqiang Shi, Qiuchen Zhao, Xiaowei Qi, Rongrong Zhao, Yongsheng Wang and Pengfei Qiu

Cancer Biology & Medicine December 2025, 20250578; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0578
Open Access
Tumor microenvironment-responsive polymeric nanoparticles for enhanced immunotherapy
Yongxin Zhang, Shaobing Zhou and Jingya Zhao

Cancer Biology & Medicine December 2025, 20250517; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0517
Open Access
From bone marrow to the tumor microenvironment: how neutrophil maturation shapes cancer immunity
Tao Shi, Yiran Cai, Hanbing Wang and Jia Wei

Cancer Biology & Medicine December 2025, 22 (12) 1431-1438; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0547

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