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LetterLetter
Open Access

Dietary restriction during active cancer therapy is associated with improved treatment response: a systematic review and meta-analysis

Kajal Agrawal, Dominic Shao Yong Goh, Ee Chern Ng, Shyn Yi Tan, Carlos Cifuentes-González, Jason Xing Kang, William K. K. Wu, Rashid N. S. Lui, Rupesh Agrawal, Yusuf Ali and Sunny H. Wong
Cancer Biology & Medicine July 2026, 20250841; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0841
Kajal Agrawal
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
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  • ORCID record for Kajal Agrawal
  • For correspondence: drkajal25{at}gmail.com sunny.wong{at}ntu.edu.sg
Dominic Shao Yong Goh
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
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Ee Chern Ng
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
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Shyn Yi Tan
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
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Carlos Cifuentes-González
2National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
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Jason Xing Kang
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
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William K. K. Wu
3Department of Anaesthesia and Intensive Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
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Rashid N. S. Lui
4Division of Gastroenterology and Hepatology, Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
5Department of Clinical Oncology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
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Rupesh Agrawal
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
2National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
6Singapore Eye Research Institute, Singapore
7Eye ACP Program, Duke NUS Medical School, Singapore
8Department of Ophthalmology, National University of Singapore, Singapore
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Yusuf Ali
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
9Clinical Research Unit, Khoo Teck Puat Hospital, National Healthcare Group, Singapore
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Sunny H. Wong
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
10Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore
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  • For correspondence: drkajal25{at}gmail.com sunny.wong{at}ntu.edu.sg
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Article Information

20250841
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2025.0841

Published By 
Cancer Biology & Medicine
History 
  • Received March 20, 2026
  • Accepted May 19, 2026
  • Published online July 13, 2026.

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  • You are currently viewing a previous version of this article (July 13, 2026 - 06:36).
  • latest version (August 10, 2026 - 00:06).
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Copyright & Usage 
Copyright: © 2026, The Authors This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License.

Author Information

Funding

  • Ong Tiong Tat Endowed Chair Professorship for Yusuf Ali. Dr. Rupesh Agrawal

    MOH-001287-00
  • Singapore National Medical Research Council Clinician Scientist Individual Research Grant

    CIRG23jan-0004
  • Large Collaborative Grant

    OFLCG22may-0009
  • Large Collaborative Grant

    OFLCG23may-0031
  • Large Collaborative Grant

    OFLCG24may-0025

The project was supported by the Lee Kong Chian School of Medicine Center for Microbiome Medicine, the Wang Lee Wah Memorial Fund, and the Student Scholarly Project. We would like to thank the Ong Tiong Tat Endowed Chair Professorship for Yusuf Ali. Dr. Rupesh Agrawal (Grant No. MOH-001287-00) is supported by the Clinician Scientist Grant from the National Medical Research Council (NMRC). Sunny Wong is supported by the Singapore National Medical Research Council Clinician Scientist Individual Research Grant (Grant No. CIRG23jan-0004), Large Collaborative Grant (Grant Nos. OFLCG22may-0009, OFLCG23may-0031, and OFLCG24may-0025).

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Cancer Biology & Medicine: 23 (8)
Cancer Biology & Medicine
Vol. 23, Issue 8
15 Aug 2026
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Dietary restriction during active cancer therapy is associated with improved treatment response: a systematic review and meta-analysis
Kajal Agrawal, Dominic Shao Yong Goh, Ee Chern Ng, Shyn Yi Tan, Carlos Cifuentes-González, Jason Xing Kang, William K. K. Wu, Rashid N. S. Lui, Rupesh Agrawal, Yusuf Ali, Sunny H. Wong
Cancer Biology & Medicine Jul 2026, 20250841; DOI: 10.20892/j.issn.2095-3941.2025.0841

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Dietary restriction during active cancer therapy is associated with improved treatment response: a systematic review and meta-analysis
Kajal Agrawal, Dominic Shao Yong Goh, Ee Chern Ng, Shyn Yi Tan, Carlos Cifuentes-González, Jason Xing Kang, William K. K. Wu, Rashid N. S. Lui, Rupesh Agrawal, Yusuf Ali, Sunny H. Wong
Cancer Biology & Medicine Jul 2026, 20250841; DOI: 10.20892/j.issn.2095-3941.2025.0841
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