LetterLetter
Open Access
Enhancing FIT-based colorectal cancer screening through risk prediction: a comparative evaluation of 17 models in a large Chinese cohort
Le Wang, Weimiao Wu, Bin Liu, Chen Zhu, Yumeng Ding, Yi Zhou, Weiwei Chen, Lijuan Dai, Xueni Chen, Yuefan Shen, Tingting Pan, Xiaohui Sun, Huizhang Li, Dong Hang, Yingying Mao, Partha Basu and Lingbin Du
Cancer Biology & Medicine March 2026, 20250702; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0702
Le Wang
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
Weimiao Wu
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
Bin Liu
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
2Department of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China
Chen Zhu
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
Yumeng Ding
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
3Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China
Yi Zhou
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
2Department of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China
Weiwei Chen
3Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China
Lijuan Dai
3Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China
Xueni Chen
3Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China
Yuefan Shen
3Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China
Tingting Pan
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
Xiaohui Sun
2Department of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China
Huizhang Li
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
Dong Hang
3Department of Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China
Yingying Mao
2Department of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China
Partha Basu
4Early Detection, Prevention & Infections Branch, International Agency for Research on Cancer (WHO), Lyon 69007, France
Lingbin Du
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China
5Zhejiang Key Laboratory of Prevention, Diagnosis and Therapy for Gastrointestinal Cancer, Hangzhou 310022, China

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In this issue
Enhancing FIT-based colorectal cancer screening through risk prediction: a comparative evaluation of 17 models in a large Chinese cohort
Le Wang, Weimiao Wu, Bin Liu, Chen Zhu, Yumeng Ding, Yi Zhou, Weiwei Chen, Lijuan Dai, Xueni Chen, Yuefan Shen, Tingting Pan, Xiaohui Sun, Huizhang Li, Dong Hang, Yingying Mao, Partha Basu, Lingbin Du
Cancer Biology & Medicine Mar 2026, 20250702; DOI: 10.20892/j.issn.2095-3941.2025.0702
Enhancing FIT-based colorectal cancer screening through risk prediction: a comparative evaluation of 17 models in a large Chinese cohort
Le Wang, Weimiao Wu, Bin Liu, Chen Zhu, Yumeng Ding, Yi Zhou, Weiwei Chen, Lijuan Dai, Xueni Chen, Yuefan Shen, Tingting Pan, Xiaohui Sun, Huizhang Li, Dong Hang, Yingying Mao, Partha Basu, Lingbin Du
Cancer Biology & Medicine Mar 2026, 20250702; DOI: 10.20892/j.issn.2095-3941.2025.0702
Jump to section
- Article
- Overall study design and analytical framework
- Identification and characteristics of colorectal cancer risk prediction models
- Discrimination and calibration performance of risk prediction models in external validation
- Screening yield and risk stratification performance for ACN
- Supporting Information
- Conflict of interest statement
- Author contributions
- Data availability statement
- References
- Figures & Data
- Info & Metrics
- References
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