Research ArticleOriginal Article
Open Access
Temporal radiomics for non-invasive preoperative prediction of pathologic complete response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
Sunyi Zheng, Shuo Wang, Ziwei Feng, Jing Liang, Jiaxin Liu, Xiaomeng Yang, Zhanshuo Zhang, Yuechen Cui, Jiping Xie, Shuxuan Fan, Jing Wang, Guoqing Liao, Haiyu Zhou, Zhaoxiang Ye, Jianyu Xiao, Lei Shi, Xiaonan Cui and Dongsheng Yue
Cancer Biology & Medicine January 2026, 20250327; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0327
Sunyi Zheng
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Shuo Wang
2Department of Lung Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Ziwei Feng
3National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Molecular Cancer Epidemiology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Jing Liang
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Jiaxin Liu
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Xiaomeng Yang
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Zhanshuo Zhang
2Department of Lung Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Yuechen Cui
2Department of Lung Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Jiping Xie
2Department of Lung Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Shuxuan Fan
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Jing Wang
4School of Public Health, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Guoqing Liao
5Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510060, China
Haiyu Zhou
5Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510060, China
Zhaoxiang Ye
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Jianyu Xiao
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Lei Shi
6Department of Radiology, Zhejiang Cancer Hospital, Hangzhou 310022, China
Xiaonan Cui
1Department of Radiology, Medical Artificial General Intelligence for Computation (MAGIC) Lab, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
Dongsheng Yue
2Department of Lung Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China

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In this issue
Temporal radiomics for non-invasive preoperative prediction of pathologic complete response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
Sunyi Zheng, Shuo Wang, Ziwei Feng, Jing Liang, Jiaxin Liu, Xiaomeng Yang, Zhanshuo Zhang, Yuechen Cui, Jiping Xie, Shuxuan Fan, Jing Wang, Guoqing Liao, Haiyu Zhou, Zhaoxiang Ye, Jianyu Xiao, Lei Shi, Xiaonan Cui, Dongsheng Yue
Cancer Biology & Medicine Jan 2026, 20250327; DOI: 10.20892/j.issn.2095-3941.2025.0327
Temporal radiomics for non-invasive preoperative prediction of pathologic complete response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
Sunyi Zheng, Shuo Wang, Ziwei Feng, Jing Liang, Jiaxin Liu, Xiaomeng Yang, Zhanshuo Zhang, Yuechen Cui, Jiping Xie, Shuxuan Fan, Jing Wang, Guoqing Liao, Haiyu Zhou, Zhaoxiang Ye, Jianyu Xiao, Lei Shi, Xiaonan Cui, Dongsheng Yue
Cancer Biology & Medicine Jan 2026, 20250327; DOI: 10.20892/j.issn.2095-3941.2025.0327
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