LetterLetter
Open Access
Phase I clinical study of humanized BCMA-single-domain antibodies targeting CAR-T in patients with relapsed or refractory multiple myeloma
Gaofeng Zheng, Ruyi Xu, Heng Mei, Xiaoyan Han, Donghua He, Yanling Weng, Cheng Wen, Zhuoxiao Cao and Zhen Cai
Cancer Biology & Medicine October 2025, 20240581; DOI: https://doi.org/10.20892/j.issn.2095-3941.2024.0581
Gaofeng Zheng
1Multiple Myeloma Treatment Center and Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
Ruyi Xu
1Multiple Myeloma Treatment Center and Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
Heng Mei
2Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Xiaoyan Han
1Multiple Myeloma Treatment Center and Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
Donghua He
1Multiple Myeloma Treatment Center and Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
Yanling Weng
1Multiple Myeloma Treatment Center and Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
Cheng Wen
3Shanghai Simnova Biotechnology Co., Ltd, Shanghai 200120, China
Zhuoxiao Cao
3Shanghai Simnova Biotechnology Co., Ltd, Shanghai 200120, China
Zhen Cai
1Multiple Myeloma Treatment Center and Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China

References
- 1.↵
- 2.↵
- 3.↵
- 4.↵
- Novak AJ,
- Darce JR,
- Arendt BK,
- Harder B,
- Henderson K,
- Kindsvogel W, et al.
- 5.↵
- Berdeja JG,
- Madduri D,
- Usmani SZ,
- Jakubowiak A,
- Agha M,
- Cohen AD, et al.
- 6.↵
- 7.↵
- 8.↵
- 9.↵
- Watanabe N,
- Mo F,
- McKenna MK.
- 10.↵
- Khan AN,
- Chowdhury A,
- Karulkar A,
- Jaiswal AK,
- Banik A,
- Asija S, et al.
- 11.↵
- 12.↵
In this issue
Phase I clinical study of humanized BCMA-single-domain antibodies targeting CAR-T in patients with relapsed or refractory multiple myeloma
Gaofeng Zheng, Ruyi Xu, Heng Mei, Xiaoyan Han, Donghua He, Yanling Weng, Cheng Wen, Zhuoxiao Cao, Zhen Cai
Cancer Biology & Medicine Oct 2025, 20240581; DOI: 10.20892/j.issn.2095-3941.2024.0581
Phase I clinical study of humanized BCMA-single-domain antibodies targeting CAR-T in patients with relapsed or refractory multiple myeloma
Gaofeng Zheng, Ruyi Xu, Heng Mei, Xiaoyan Han, Donghua He, Yanling Weng, Cheng Wen, Zhuoxiao Cao, Zhen Cai
Cancer Biology & Medicine Oct 2025, 20240581; DOI: 10.20892/j.issn.2095-3941.2024.0581
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