Article Figures & Data
Figures
- 1
Immunohistochemical staining for CENP-H expression in uterine cervical cancer and paraneoplastic tissues. A: Absence of CENP-H expression in paraneoplastic tissues; B: Low expression of CENP-H in uterine cervical cancer; C: High expression of CENP-H in uterine cervical cancer (200 ×).
- 2
Comparison of the survival rates between the group with high CENP-H expression and that with low CENP-H expression in the 62 UCC patients.
Tables
Characteristics Cases CENP-H P Low expression (%) High expression (%) Age (years) <60 29 11 (37.9) 18 (62.1) 0.906 ≥60 33 13 (39.4) 20 (60.6) Tumor size (cm) ≥4 24 6 (25.0) 18 (75.0) 0.001 <4 38 18 (47.4) 20 (52.6) Stage I/II 26 14 (53.8) 12 (46.2) 0.038 III/IV 36 10 (27.8) 26 (72.2) T-staging T1/T2 23 11 (47.8) 12 (52.2) 0.258 T3/T4 39 13 (33.3) 26 (66.7) Nodal metastasis Existent 27 11 (40.7) 16 (59.3) 0.773 Nonexistent 35 13 (37.1) 22 (62.9) - 2
Univariate and multivariate cox regression analysis of the prognostic factors of UCC patients.
Univariate analysis Multivariable analysis Cases P Regression coefficient (SE) P Coefficient of relative risk 95% CI Stage I/II 26 0.003 1.104 (0.376%) 0.001 2.135 1.271-3.586 III/IV 36 CENP-H High expression 38 0.001 0.917 (0.358%) 0.002 1.490 1.113–1.995 Low expression 24 T-staging T1/T2 23 0.004 0.697 (0.114%) 0.007 1.280 0.971-1.428 T3/T4 39 Node metastasis Positive 27 0.000 1.677 (0.370%) 0.004 2.892 1.326-5.278 Negative 35
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