Defining a Subgroup Treatable for Laparoscopic Surgery in Poorly Differentiated Early Gastric Cancer: the Role of Lymph Node Metastasis

Article Figures & Data

Table 1

Univariate analysis of potential risk characteristics for lymph node metastasis.

Characteristics	Lymph node metastasis positive number (%)	P
Gender
Male (n=49)	6 (12.2)	0.523
Female (n=21)	4 (19.0)	0.523
Age, years
<60 (n = 65)	9 (13.8)	0.748
≥60 (n = 5)	1 (20.0)	0.748
Family history
Positive (n = 1)	0	0.704
Negative (n = 69)	10 (14.5)	0.704
Number of tumors
Single (n = 68)	10 (14.7)	0.588
Multitude (n = 2)	0	0.588
Location
Upper (n = 16)	3 (20.0)	0.683
Middle (n=4)	0
Lower (n = 50)	7 (14.0)
Tumor size, cm
≤2 (n=45)	2 (4.4)	0.008
>2 (n=25)	8 (32.0)	0.008
Macroscopic type
I (n=0)	0	0.171
II (n=55)	8 (13.6)
III (n = 15)	2 (40.0)
Depth of invasion
Mucosa (n=46)	2 (4.3)	0.006
Submucosa (n = 24)	8 (33.3)	0.006
Lymphatic vessel involvement
Positive (n=11)	6 (54.5)	0.001
Negative (n=59)	4 (6.8)	0.001

Table 2

Multivariate analysis of potential risk factors for lymph node metastasis.

Characteristics	HR	95%CI	P
Tumor size, cm
≤2 (n=45)	6.235	1.150–35.112	0.038
>2 (n=25)	6.235	1.150–35.112	0.038
Depth of invasion
Mucosa (n=46)	13.354	1.371–97.014	0.031
Submucosa (n = 24)	13.354	1.371–97.014	0.031
Lymphatic vessel involvement
Positive (n = 11)	32.012	1.657–185.397	0.017
Negative (n = 59)	32.012	1.657–185.397	0.017