Article Figures & Data
Figures
- Fig. 1.
Positive expressions of the COX-2 and HER-2 protein in adenocarcinoma (ACA) of the lung and squamous carcinoma (SqCa) of the lung. A, COX-2 protein (ACA); B, HER-2 protein (ACA); C, COX-2 protein (SqCa); D, HER-2 protein (SqCa).
- Fig. 2.
Survival curves in the groups with an over and a low expressions of COX-2/HER-2.
Tables
Tissue n COX-2 P HER-2 P -/+ ++/+++ -/+ ++/+++ Normal pulmonary tissue 10 10 0 0.000 10 0 0.013 Paraneoplasticpulmonary tissue 16 12 4 0.000 14 2 0.037 Lung cancer 54 13 41 32 22 - Table 2.
Relationship between the expression of COX-2 & HER-2 protein and clinicopathologic features of LC.
Characteristics n COX-2 P HER-2 P -/+ ++/+++ -/+ ++/+++ Sex 0.553 0.369 Male 38 10 28 24 14 Female 16 3 13 8 8 Smoking history 0.016 0.087 Yes 32 4 28 22 10 No 22 9 13 10 12 Histological grades 0.000 0.000 Grade I 14 11 3 13 1 Grade II 25 2 23 15 10 Grade III 15 0 15 4 11 Pathlogical types 0.255 0.004 ACA 30 9 21 23 7 SqCa 24 4 20 9 15 TNM stages 0.000 0.000 Stage I 13 9 4 0 13 Stage II 30 4 26 30 0 Stage IIIa 11 0 11 2 9 Lymphatic metastasis 0.028 0.033 Yes 38 6 32 19 19 No 16 7 9 13 3 - Table 3.
Univariate analysis of the relationship between the clinical parameters and prognosis of NSCLC patients.
Clinical parameters Groups P Age (years) ≤ 50 > 50 0.872 Smoking history No Yes 0.518 Pathological types SqCa ACA 0.541 TNM stages Stage I-II Stage IIIa 0.034 Lymphatic metastasis No Yes 0.012 Histological grades Grade I Grade II-III 0.004 COX-2/HER-2 Over Exp Low Exp 0.000
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