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Research ArticleResearch Article

Clinical Research Regarding the Ratio of Lymph Node Metastasis and the Reasonable Extent of Lymphadenectomy in Middle Third Thoracic Esophageal Squamous Cell Carcinoma

Ming-ran XIE, Peng LIN, Xu ZHANG, Jie-xin CHEN, Yong-bin LIN, Zhe-sheng WEN, Tie-hua RONG, Xiao-dong LI, Jun-ye WANG and Hui YU
Clinical Oncology and Cancer Research February 2010, 7 (1) 33-38; DOI: https://doi.org/10.1007/s11805-010-0033-y
Ming-ran XIE
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Peng LIN
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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  • For correspondence: linpengsir{at}hotmail.com
Xu ZHANG
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Jie-xin CHEN
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Yong-bin LIN
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Zhe-sheng WEN
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Tie-hua RONG
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Xiao-dong LI
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Jun-ye WANG
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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Hui YU
State Key Laboratory of Oncology in South China, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
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    Fig. 1

    Comparison of the survival rates of patients in groups with N0, N1 (A) and N1 (B).

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    Table 1.

    Characteristics of lymph node metastasis in 129 patients with middle thoracic esophageal carcinoma.

    Sites of lymph node involvementNo. of the lymph nodes detectedNo. of lymph nodes metastasizedRLNM (%)
    ThoraxAdjacent to right RLN2784616.5
    Adjacent to left RLN190126.3
    Adjacent to right trachea (R2, R4)296268.8
    Aortopulmonary fenestration13353.8
    Inferior to tracheal protuberance3583810.6
    Periesophageal4027418.4
    Pulmonary hilar lymph node12732.4
    Diaphragmatic muscle7800
    AbdomenBy gastric cardia (left, right)2834114.5
    Surrounding left gastric vessels2994214.0
    Lesser gastric curvature1692011.8
    Greater gastric curvature9855.1
    Surrounding the celiac artery6534.6
    • View popup
    Table 2.

    Relationship among LMR, the depth of tumor infiltration, tumor size, and the degree of tumor cell differentiation.

    ItemsnNo. of cases with lymph nodes metastasisLMR (%)Pχ2
    Depth of tumor infiltration0.00116.695
        T18112.5
        T226934.6
        T3875664.4
        T48787.5
    Size of tumor (cm)0.0079.995
        ≤ 329931.0
        3-5683855.9
        ≥ 5322681.3
    Degree of tumor cell differentiation0.00510.545
        G1321134.4
        G2603558.3
        G3372773.0
    • View popup
    Table 3.

    The 1-, 3- and 5-year survival rates in 129 patients with different rates of lymph node metastasis.

    GroupsnSurvival rate (%)
    1-year3-year5-year
    N05689.366.750.4
    N1 (A)4977.444.231.0
    N1 (B)2461.430.76.8
    • P = 0.000

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Cancer Biology and Medicine: 7 (1)
Clinical Oncology and Cancer Research
Vol. 7, Issue 1
1 Feb 2010
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Clinical Research Regarding the Ratio of Lymph Node Metastasis and the Reasonable Extent of Lymphadenectomy in Middle Third Thoracic Esophageal Squamous Cell Carcinoma
Ming-ran XIE, Peng LIN, Xu ZHANG, Jie-xin CHEN, Yong-bin LIN, Zhe-sheng WEN, Tie-hua RONG, Xiao-dong LI, Jun-ye WANG, Hui YU
Clinical Oncology and Cancer Research Feb 2010, 7 (1) 33-38; DOI: 10.1007/s11805-010-0033-y

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Clinical Research Regarding the Ratio of Lymph Node Metastasis and the Reasonable Extent of Lymphadenectomy in Middle Third Thoracic Esophageal Squamous Cell Carcinoma
Ming-ran XIE, Peng LIN, Xu ZHANG, Jie-xin CHEN, Yong-bin LIN, Zhe-sheng WEN, Tie-hua RONG, Xiao-dong LI, Jun-ye WANG, Hui YU
Clinical Oncology and Cancer Research Feb 2010, 7 (1) 33-38; DOI: 10.1007/s11805-010-0033-y
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Keywords

  • esophagus cancer
  • lymph nodes
  • metastasis
  • lymphadenectomy

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