Analysis of Prognostic Factors of Esophageal and Gastric Cardiac Carcinoma Patients after Radical Surgery Using Cox Proportional Hazard Model-A Random Sampling Study from the Fourth Hospital of Hebei Medical University during the Period of 1996-2004

Article Figures & Data

Table 1.

Univariate analysis of prognostic factors of 906 patients with esophageal carcinoma and carcinoma of gastric cardia after surgery.

Factors	Wald	P	RR	95.0% CI for RR
Age (years)	10.061	0.007
≤ 50	2.506		0.1
51-60	9.759	0.002	0.798	0.663 ± 0.963
> 60		0.113	1.337	0.934 ± 1.916
Tumor size (cm)	40.165	0.000
≤ 3			1.000
3.1-5	13.743	0.000	2.676	1.590 ± 4.502
5.1-7	11.134	0.001	2.586	1.480 ± 4.518
> 7	36.299	0.000	5.416	3.126 ± 9.383
Pathologic type	25.928	0.000
SqCa			1.000
Adenocarcinoma	.809	0.369	1.151	0.847 ± 1.563
USCC	24.006	0.000	3.874	2.254 ± 6.660
Mucinous adenocarcinoma	1.951	0.163	1.895	0.773 ± 4.648
Others	1.620	0.203	1.706	0.749 ± 3.884
No. of lymph node metastasis	45.295	0.000
0			1.000
1-3	22.699	0.000	2.094	1.545 ± 2.838
> 3	36.954	0.000	3.608	2.385 ± 5.456
TNM staging	28.258	0.000
Stage-0 & I			1.000
Stage-II	6.487	0.011	2.591	1.245 ± 5.393
Stage-III	15.935	0.000	4.380	2.121 ± 9.045
Stage-IV	17.583	0.000	5.162	2.397 ± 11.118
Depth of infiltration	21.650	0.001
Tumor in situ			1.000
Lamina propria, Submucosa	1.202	0.273	.368	0.061 ± 2.200
Superficial muscular layer	0.885	0.347	1.835	0.518 ± 6.504
Deep muscular layer	0.303	0.582	1.411	0.414 ± 4.817
Fibrous membrane (Serous membrane)	3.022	0.082	2.776	0.878 ± 8.774
Surrounding soft tissue	3.866	0.049	3.182	1.004 ± 10.087
Encroachment of localorgans	27.798	0.000
Negative			1.000
Positive			2.382	1.725 ± 3.290

Table 2.

Multivariate analysis of prognostic factors of 906 patients with esophageal carcinoma and carcinoma of gastric cardia after surgery.

Factor	β	SE	Wald	P	RR	95.0% CI for RR
Factor	β	SE	Wald	P	RR	Lower	Upper
Pathologic type			22.338	0.000
SqCa					1.000
Adenocarcinoma	-0.115	0.203	0.319	0.572	0.891	0.598	1.328
USCC	1.212	0.285	18.042	0.000	3.359	1.920	5.876
Mucinous adenocarcinoma	0.296	0.473	0.393	0.531	1.345	0.532	3.401
Others	0.391	0.426	0.842	0.359	1.479	0.641	3.410
TNM staging			8.005	0.046
Stage-0 & I					1.000
Stage-II	0.790	0.379	4.349	0.037	2.204	1.049	4.633
Stage-III	1.053	0.388	7.353	0.007	2.865	1.339	6.131
Stage-IV	0.904	0.454	3.968	0.046	2.470	1.015	6.011
No. of lymph node metastasis			16.314	0.000
0					1.000
1-3	0.439	0.195	5.067	0.024	1.552	1.058	2.275
> 3	1.020	0.253	16.312	0.000	2.774	1.691	4.552
Encroachment of localorgans			17.882	0.000
Negative					1.000
Positive	0.718	0.170	17.882	0.000	2.050	1.470	2.858