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Research ArticleResearch Article

Analysis of 6 Cases of Stromal Sarcoma of the Breast

Yizi Cong, Juntian Liu and Zhilong Jia
Clinical Oncology and Cancer Research April 2009, 6 (2) 147-151; DOI: https://doi.org/10.1007/s11805-009-0147-2
Yizi Cong
No. 2 Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
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Juntian Liu
No. 2 Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
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  • For correspondence: ljt641024{at}yahoo.cn
Zhilong Jia
No. 2 Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
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  • The tumor at the upper outer quadrant of the left breast, with skin ulcer (Case 4)
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    Fig. 1.

    The tumor at the upper outer quadrant of the left breast, with skin ulcer (Case 4)

  • SSB presenting a stromal-sarcoma-like form (fibrosarcoma), H&E × 200 (Case 4)
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    Fig. 2.

    SSB presenting a stromal-sarcoma-like form (fibrosarcoma), H&E × 200 (Case 4)

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    Table 1.

    The clinical feature, treatment and prognosis of 6 patients with SSB

    CaseAge, yearsTumor (cm)SiteSymptoms and signsTNM stagingPrevious local excisionMode of surgeryPathological resultsChemotherapyRelapse & metastasisFollow-up (mon)
    1208 × 8Central area of right breastRapid growth of the tumor, with dark purple on surface of the skin and without pain; the tumor at palpation was lobulated, with a hard texture or inhomoge-nous hardness, and blurred boundary from the normal tissue, the lesions adhering to the skin and chestT4N0M0 Stage IIIBRelapse after 2 local resections of the tumorRadical resectionMucinous degeneration of stromal sarcoma, ln: 0/8NoneMetastases in bilateral lungs 7 months after surgery8
    2353 × 2UIQ of right breastRapid growth of the tumor, without pain; a 5-cm radial incision at UIQT2N0M0 Stage IIARelapse after 2 local resections of the tumor; an intra-muscular capillary tumorRadical resectionStromal s arcoma, ln: 0/62(IFO + EPI) × 6None12
    335Failure of achieving the staging criteri-onMUOQ of right breastA 5-cm transverse incision at MUOQ of right breastTxN0M0Relapse after 2 local resections of the tumor; a fibrosar-coma of the breastExcision of total breastStromal sarcomaNoneNone204
    44115 × 13UOQ of left breastRapid growth of the tumor, with discontinu-ous dull pain and blurred boundary, fixation, scytitis of whole breast, a 5×6-cm ulcer at upper left quadrant, a stellate ganglionT4N0M0 Stage IIIBNoneExcision of total breastStromal sarcoma(CTX + DTIC + ADM + VCR) × 6None41
    5463.5 × 3UOQ of left breastNo pain and nipple discharge were found 2 months after discovery of the tumor; The surface of tumor was smooth at palpation, with a hard texture and a better mobility, and a 0.5×0.6-cm axillary nodesT2N1M0 Stage IIBNoneExcision of total breast + lower armpitStromal sarcoma with focal ossification, ln: 0/22CAF × 6None60
    6556 × 6UOQ of right breastNo pain andnipple discharge were found; The lump had a hard texture, a blurred boundary and a poor mobilityT3N0M0 Stage IIBRelapse 4 months after excision of the tumorExcision of total breast + lower armpitStromal sarcoma of low malignancy, ln: 0/10NoneNone32
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Cancer Biology and Medicine: 6 (2)
Clinical Oncology and Cancer Research
Vol. 6, Issue 2
1 Apr 2009
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Analysis of 6 Cases of Stromal Sarcoma of the Breast
Yizi Cong, Juntian Liu, Zhilong Jia
Clinical Oncology and Cancer Research Apr 2009, 6 (2) 147-151; DOI: 10.1007/s11805-009-0147-2

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Analysis of 6 Cases of Stromal Sarcoma of the Breast
Yizi Cong, Juntian Liu, Zhilong Jia
Clinical Oncology and Cancer Research Apr 2009, 6 (2) 147-151; DOI: 10.1007/s11805-009-0147-2
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Keywords

  • breast neoplasm
  • stromal sarcoma
  • recurrence
  • therapy

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