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Research ArticleResearch Article

HIF-1α siRNA Leads to Apoptosis of Pancreatic Cancer Cells under Hypoxic Conditions

Chuangui Chen, Jianqiu Chen and Jinjin Sun
Clinical Oncology and Cancer Research February 2009, 6 (1) 10-15; DOI: https://doi.org/10.1007/s11805-009-0010-5
Chuangui Chen
1Department of Surgery, the Second Hospital of Tianjin Medical University, TianJin 300211, China.
2Department of Esophageal Cancer, TianJin Medical University Cancer Institute & Hospital, TianJin 300060, China.
3Department of Surgery, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.
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Jianqiu Chen
1Department of Surgery, the Second Hospital of Tianjin Medical University, TianJin 300211, China.
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  • For correspondence: tracycheng2008{at}yahoo.com.cn
Jinjin Sun
1Department of Surgery, the Second Hospital of Tianjin Medical University, TianJin 300211, China.
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Article Information

vol. 6 no. 1 10-15
DOI 
https://doi.org/10.1007/s11805-009-0010-5

Published By 
Cancer Biology & Medicine
History 
  • Revision received December 1, 2008
  • Accepted January 15, 2009
  • Published online February 1, 2009.

Copyright & Usage 
Copyright © 2009 by Tianjin Medical University Cancer Institute & Hospital and Springer

Author Information

  1. Chuangui Chen1,2,3
  1. 1Department of Surgery, the Second Hospital of Tianjin Medical University, TianJin 300211, China.
  2. 2Department of Esophageal Cancer, TianJin Medical University Cancer Institute & Hospital, TianJin 300060, China.
  3. 3Department of Surgery, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.
  1. Jianqiu Chen1⇑
  1. 1Department of Surgery, the Second Hospital of Tianjin Medical University, TianJin 300211, China.
  1. Correspondence to: Jianqiu Chen E-mail: tracycheng2008{at}yahoo.com.cn
  1. Jinjin Sun1
  1. 1Department of Surgery, the Second Hospital of Tianjin Medical University, TianJin 300211, China.
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Cancer Biology and Medicine: 6 (1)
Clinical Oncology and Cancer Research
Vol. 6, Issue 1
1 Feb 2009
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HIF-1α siRNA Leads to Apoptosis of Pancreatic Cancer Cells under Hypoxic Conditions
Chuangui Chen, Jianqiu Chen, Jinjin Sun
Clinical Oncology and Cancer Research Feb 2009, 6 (1) 10-15; DOI: 10.1007/s11805-009-0010-5

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HIF-1α siRNA Leads to Apoptosis of Pancreatic Cancer Cells under Hypoxic Conditions
Chuangui Chen, Jianqiu Chen, Jinjin Sun
Clinical Oncology and Cancer Research Feb 2009, 6 (1) 10-15; DOI: 10.1007/s11805-009-0010-5
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Keywords

  • recombinant adeno-associated virus (rAAV)
  • hypoxia inducible factor (HIF)
  • small interference RNA (siRNA)
  • proliferation
  • apoptosis

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