Research ArticleResearch Article

Association of the p73 Gene G4C14-to-A4T14 Polymorphism with Increased Gastric Cancer Risk in a Northwestern Chinese Population

Weihua Zhang, Xudong Wang, Xiaodong Xie, Fengxia Guo, Rong Yang, Yuhua Liu, Shijian Xu and Yajun Yang
Chinese Journal of Clinical Oncology June 2008, 5 (3) 157-160; DOI: https://doi.org/10.1007/s11805-008-0157-5

References

  1. ↵
    1. Sun X,
    2. Mu R,
    3. Zhou Y, et al.
    1990-1992 mortality of stomach cancer in China. Zhonghua Zhong Liu Za Zhi 2002; 24: 4-8 (Chinese).
    OpenUrlPubMed
  2. ↵
    1. Oren M.
    Lonely no more: p53 finds its kin in a tumor suppressor haven. Cell 1997; 90: 829-832.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    1. Cai YC,
    2. Yang GY,
    3. Nie Y, et al.
    Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53. Carcinogenesis 2000; 21: 683–689.
    OpenUrlCrossRefPubMedWeb of Science
  4. ↵
    1. White E,
    2. Prives C.
    DNA damage enables p73. Nature 1999; 399: 734–735.
    OpenUrlPubMed
  5. ↵
    1. Craveiro R,
    2. Costa S,
    3. Pinto D, et al.
    TP73 alterations in cervical carcinoma. Cancer Genetics and Cytogenetics 2004; 150: 116-121.
    OpenUrlCrossRefPubMed
  6. ↵
    1. Nomoto S,
    2. Haruki N,
    3. Kondo M, et al.
    Search for mutations and examination of allelic expression imbalance of the p73 gene at 1q36.33 in human lung cancers. Cancer Res 1998; 58: 1380–1383.
    OpenUrlAbstract/FREE Full Text
  7. ↵
    1. Mai M,
    2. Yokomizo A,
    3. Qian C, et al.
    Activation of p73 silent allele in lung cancer. Cancer Res 1998; 58: 2347–2349.
    OpenUrlAbstract/FREE Full Text
  8. ↵
    1. Niwa Y,
    2. Amajima H,
    3. Atsuta Y, et al.
    Genetic polymorphisms of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese. Cancer Letters 2004; 205: 55-60.
    OpenUrlCrossRefPubMedWeb of Science
  9. ↵
    1. Niwa Y,
    2. Hirose K,
    3. Matsuo K, et al.
    Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects. Cancer Letters 2005; 219: 183–190.
    OpenUrlCrossRefPubMedWeb of Science
    1. Li GJ,
    2. Sturgis EM,
    3. Wang LE, et al.
    Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis 2004; 25: 1911-1916.
    OpenUrlCrossRefPubMedWeb of Science
    1. Pfeifer D,
    2. Arbman G,
    3. Sun XF.
    Polymorphism of the p73 gene in relation to colorectal cancer risk and survival. Carcinogenesis 2005; 26: 103-107.
    OpenUrlCrossRefPubMedWeb of Science
  12. ↵
    1. Li GJ,
    2. Wang LE,
    3. Chamberlain RI, et al.
    p73 G4C14-to-A4T14 Polymorphism and Risk of Lung Cancer. Cancer Res 2004; 64: 6863-6866.
    OpenUrlAbstract/FREE Full Text
  13. ↵
    1. Hamajima N,
    2. Matsuo K,
    3. Suzuki T, et al.
    No association of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro polymorphism with the risk of digestive tract cancers in Japanese. Cancer Letters 2002; 181: 81-85.
    OpenUrlCrossRefPubMedWeb of Science
  14. ↵
    1. Ge H,
    2. Wang YM,
    3. Cao YY, et al.
    Correlation of p73 polymorphisms to genetic susceptibilities to esophageal carcinoma and gastric cardiac carcinoma. Ai Zheng 2006; 25:1351-1355 (Chinese).
    OpenUrlPubMed
  15. ↵
    1. Laurén P.
    The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. Acta Path Micorbiol Scandinav 1965; 64: 31–49.
    OpenUrl
  16. ↵
    1. Hamajima N,
    2. Saito T,
    3. Matsuo K, et al.
    Polymorphism chain reaction with confronting two-pair primers for polymorphism genotyping. Jpn J Cancer Res 2000; 91: 865–868.
    OpenUrlCrossRefWeb of Science
  17. ↵
    1. Zhu J,
    2. Jiang J,
    3. Zhou W, et al.
    The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res 1998; 58: 5061-5065.
    OpenUrlAbstract/FREE Full Text
  18. ↵
    1. Mai M,
    2. Qian C,
    3. Yokomizo A, et al.
    Loss of imprinting and allele switching of p73 in renal cell carcinoma. Oncogene 1998; 17: 1739–1741.
    OpenUrlCrossRefPubMedWeb of Science
  19. ↵
    1. Liu ML,
    2. Taketani T,
    3. Li RS, et al.
    Loss of p73 gene expression in lymphoid leukemia cell lines is associated with hypermethylation. Leukemia Res 2001; 25: 441–447.
    OpenUrlCrossRefPubMed
  20. ↵
    1. Ichimiya S,
    2. Nimura Y,
    3. Kageyama H, et al.
    p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent. Oncogene 1999; 18: 1061–1066.
    OpenUrlCrossRefPubMedWeb of Science
  21. ↵
    1. Kang MJ,
    2. Park BJ,
    3. Byun DS, et al.
    Loss of imprinting and elevated expression of wild-type p73 in human gastric adenocarcinoma. Clin. Cancer Res 2000; 6: 1767-1771.
    OpenUrl
    1. Zaika AI,
    2. Kovalev S,
    3. Marchenko ND, et al.
    Over-expression of the wild type p73 gene in breast cancer tissues and cell lines. Cancer Res 1999; 59: 3257–3263.
    OpenUrlAbstract/FREE Full Text
    1. Sunahara M,
    2. Ichimiya S,
    3. Nimura Y, et al.
    Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas. Int J Oncol 1998; 13: 319–323.
    OpenUrlPubMedWeb of Science
    1. Kovalev S,
    2. Marchenko N,
    3. Swendeman S, et al.
    Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines. Cell Growth Differ 1998; 9: 897–903.
    OpenUrlAbstract
    1. Kroiss MM,
    2. Bosserhoff AK,
    3. Vogt T, et al.
    Loss of expression or mutations in the p73 tumour suppressor gene are not involved in the pathogenesis of malignant melanomas. Melanoma Res 1998; 8: 504–509.
    OpenUrlCrossRefPubMedWeb of Science
    1. Chi SG,
    2. Chang SG,
    3. Lee SJ, et al.
    Elevated and biallelic expression of p73 is associated with progression of human bladder cancer. Cancer Res 1999; 59: 2791–2793.
    OpenUrlAbstract/FREE Full Text
    1. Yokomizo A,
    2. Mai M,
    3. Tindall DJ, et al.
    Overexpression of the wild type p73 gene in human bladder cancer. Oncogene 1999; 18: 1629–1633.
    OpenUrlCrossRefPubMedWeb of Science
    1. Tannapfel A,
    2. Wasner M,
    3. Krause K, et al.
    Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma. J Natl Cancer Inst 1999; 91: 1154–1158.
    OpenUrlCrossRefPubMedWeb of Science
    1. Ng SW,
    2. Yiu GK,
    3. Liu Y, et al.
    Analysis of p73 in human borderline and invasive ovarian tumor. Oncogene 2000; 19: 1885–1890.
    OpenUrlCrossRefPubMedWeb of Science
  30. ↵
    1. Dominguez G,
    2. Silva JM,
    3. Silva J, et al.
    Wild type p73 overexpression and high-grade malignancy in breast cancer. Breast Cancer Res Tr 2001; 66: 183–190.
    OpenUrl
    1. Takahashi H,
    2. Ichimiya S,
    3. Nimura Y, et al.
    Mutation, allelotyping, and transcription analyses of the p73 gene in prostatic carcinoma. Cancer Res 1998; 58: 2076–2077.
    OpenUrlAbstract/FREE Full Text
  32. ↵
    1. Yang A,
    2. Walker N,
    3. Bronson R, et al.
    p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature 2000; 404: 99–103.
    OpenUrlCrossRefPubMedWeb of Science
  33. ↵
    1. Marin MC,
    2. Jost CA,
    3. Irwin MS, et al.
    Viral oncoproteins discriminate between p53 and the p53 homolog p73. Mol. Cell Biol 1998; 18: 6316-6324.
    OpenUrlAbstract/FREE Full Text
  34. ↵
    1. Roth J,
    2. Konig C,
    3. Wienzek S, et al.
    Inactivation of p53 but not p73 by adenovirus type 5 E1B 55-kilodalton and E4 34-kilodalton oncoproteins. J Virol 1998; 72: 8510-8516.
    OpenUrlAbstract/FREE Full Text
  35. ↵
    1. Hiyama T,
    2. Tanaka S,
    3. Kitadai Y, et al.
    p53 codon 72 in patients with Helicobacter pylori-associated chronic gastritis. Intern J Cancer 2002; 100: 304-308.
    OpenUrlCrossRefPubMedWeb of Science
  36. ↵
    1. Kaneko S,
    2. Yoshimura T.
    Time trend analysis of gastric cancer incidence in Japan by histological types, 1975-1989. Br J Cancer 2001; 84: 400-405.
    OpenUrlCrossRefPubMedWeb of Science
  37. ↵
    1. Zhang WH,
    2. Wang XL,
    3. Zhou J, et al.
    Association of interleukin-1B (IL-1B) gene polymorphisms with risk of gastric cancer in Chinese population. Cytokine 2005; 30: 378-381.
    OpenUrlCrossRefPubMedWeb of Science
  38. ↵
    1. Nimura Y,
    2. Mihara M,
    3. Ichiyama S, et al.
    p73, a gene related to p53, is not mutated in esophageal carcinomas. Int J Cancer 1998; 78: 437–440.
    OpenUrlCrossRefPubMedWeb of Science
    1. Stiewe T,
    2. Putzer BM.
    Role of p73 in malignancy: tumor suppressor or oncogene? Cell Death Differ 2002; 9: 237–245.
    OpenUrlCrossRefPubMedWeb of Science
  40. ↵
    1. Yokozaki H,
    2. Shitara Y,
    3. Fujimoto J, et al.
    Alterations of p73 preferentially occur in gastric adenocarcinomas with foveolar epithelial phenotype. Int J Cancer 1999; 83: 192-196.
    OpenUrlCrossRefPubMed
  41. ↵
    1. Tannapfel A,
    2. Schmelzer S,
    3. Benidke M, et al.
    Expression of the p53 homologues p63 and p73 in multiple simultaneous gastric cancer. J Pathol 2001; 195: 163-170.
    OpenUrlCrossRefPubMed
Back to top

In this issue

Print
Download PDF
Email Article
Citation Tools

Jump to section

Keywords