Research ArticleResearch Article

Association of the p73 Gene G4C14-to-A4T14 Polymorphism with Increased Gastric Cancer Risk in a Northwestern Chinese Population

Weihua Zhang, Xudong Wang, Xiaodong Xie, Fengxia Guo, Rong Yang, Yuhua Liu, Shijian Xu and Yajun Yang
Chinese Journal of Clinical Oncology June 2008, 5 (3) 157-160; DOI: https://doi.org/10.1007/s11805-008-0157-5

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Tables

  • Table 1.

    Common characteristics of the studied GC cases and the controls (n, %).

    GC
    n = 385    		Controls
    n = 412    		χ2P
    Age, years0.17> 0.50
        ≤50127 (33.0)130 (31.5)
        >50258 (67.0)282 (68.4)
    Sex0.04> 0.75
        Male308 (80.0)332 (80.6)
        Female77 (20.0)80 (19.4)
  • Table 2.

    p73 gene G4A genotype frequencies in controls, GC cases and in different histological subtypes of GC in a studied Chinese population (n, %).

    p73 G4A
    LocusAT/ATAT/GCGC/GC
    Controls (n = 412)116 (28.1)194 (47.1)102 (24.8)
    GC cases (n = 373)82 (22.0)168 (45.0)123 (33.0)
    OR (95% CI)1.001.23(0.86~1.74)1.71(1.16~2.51)
    Diffuse-type GC (n = 295)64 (21.7)126 (42.7)105 (35.6)
    OR (95% CI)1.001.18 (0.81~1.72)1.87 (1.24~2.81)
    Intestinal type GC (n = 78)18 (23.1)42 (53.8)18 (23.1)
    OR (95% CI)1.001.40 (0.70~2.54)1.14 (0.56~2.30)
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