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Research ArticleResearch Article

Spontaneous Tumor Lysis Syndrome and Secondary Thrombotic Thrombocytopenic Purpura in Early Stage Colorectal Cancer

Saad Usmani, Joel Appel, Zainab Shahid and Husain Saleh
Chinese Journal of Clinical Oncology April 2008, 5 (2) 150-153; DOI: https://doi.org/10.1007/s11805-008-0150-z
Saad Usmani
1Hematology-Oncology, University of Connecticut Health Center, Farmington, Connecticut, USA.
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  • For correspondence: saadzu{at}yahoo.com
Joel Appel
2Department of Internal Medicine/Hematology Oncology, Sinai-Grace Hospital, Wayne State University, Detroit, Michigan, USA.
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Zainab Shahid
3Department of Internal Medicine, Sinai-Grace Hospital/Detroit Medical Center, Wayne State University, Detroit, Michigan, USA.
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Husain Saleh
4Department of Pathology, Sinai-Grace Hospital/Detroit Medical Center, Associate Professor of Pathology, Wayne State University, Detroit, Michigan, USA.
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    Fig.1.

    Photomicrograph of peripheral blood smear showing several schistocytes (erythrocytes fragments), anisocytosis, hypochromasia and microcytes (Wright Giemsa stain, oil/×1,000).

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    Fig.2.

    Low power magnification of the sigmoid colon mass showing infiltrating tumor glands and nests into the muscle propriety (H&E stain, ×4).

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    Fig.3.

    Medium power magnification showing colon carcinoma with invasive irregular glands surrounded by desomplastic stroma (H&E stain, ×10).

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    Graph.1

    Trend of hemoglobin levels during hospitalization.

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    Graph.2

    Trend of platelet counts during hospitalization.

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    Graph.3

    Trend of chemistry profile during hospitalization.

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Cancer Biology and Medicine: 5 (2)
Chinese Journal of Clinical Oncology
Vol. 5, Issue 2
April 2008
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Spontaneous Tumor Lysis Syndrome and Secondary Thrombotic Thrombocytopenic Purpura in Early Stage Colorectal Cancer
Saad Usmani, Joel Appel, Zainab Shahid, Husain Saleh
Chinese Journal of Clinical Oncology Apr 2008, 5 (2) 150-153; DOI: 10.1007/s11805-008-0150-z

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Spontaneous Tumor Lysis Syndrome and Secondary Thrombotic Thrombocytopenic Purpura in Early Stage Colorectal Cancer
Saad Usmani, Joel Appel, Zainab Shahid, Husain Saleh
Chinese Journal of Clinical Oncology Apr 2008, 5 (2) 150-153; DOI: 10.1007/s11805-008-0150-z
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Keywords

  • tumor lysis syndrome
  • thrombotic thrombocytopenic purpura
  • Colorectal cancer
  • acute renal failure

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