Article Figures & Data
Figures
- Fig.1.
Negative expression of the β-tubulin protein in normal breast tissue( IHC S-P, ×40).
- Fig.2.
Positive expression of the β-tubulin protein in ADH ( IHC S-P, ×200).
- Fig.3.
Positive expression of the β-tubulin protein in DCIS( IHC S-P, ×100).
- Fig.4.
Positive expression of the β-tubulin protein in IDC( IHC S-P, ×200).
Tables
Type n - + ++ +++ Normal tissuea 30 5 9 12 4 Premalignant lesionb 50 2 11 26 11 DCISc 50 0 5 25 20 IDCd 50 0 6 18 26 Total 180 7 31 81 61 ↵There was statistically significant differences among the 4 tissue types (χ2 = 25.381, P < 0.05). Comparison of any two groups: a:b, z = -1.992, P < 0.05; a:c, z= -3.807, P < 0.05; a:d, z = -4.161, P < 0.05; b:c, z = -2.469, P < 0.05; b:d, z = -3.120, P < 0.05; c:d, z = -0.909, P > 0.05.
Group n - + ++ +++ Low grade 26 0 4 13 9 High grade 24 0 1 12 11 Total 50 0 5 25 20 There was not a statistically significant difference between the two groups (z = -1.122, P > 0.05), and the β-tubulin expression was not significantly correlated to the nuclear grade of DCIS (P > 0.05).
Group n - + ++ +++ Low grade 35 0 4 13 18 High grade 15 0 2 5 8 Total 50 0 6 18 26 The difference between the two groups was not significant (z = -0.036, P > 0.05), and there was not a relation of β-tubulin expression to histological grade of IDC (P > 0.05).
- Table 4.
Expression of β-tubulin in IDC with and without metastasis in axillary lymph nodes.
Group n - + ++ +++ Metastasis 27 0 1 14 12 No metastasis 23 0 2 17 4 Total 50 0 3 31 16 A significant difference was observed between the two groups (z = -2.0290, P < 0.05), and the β-tubulin expression was positively correlated to metastasis of axillary lymph nodes (r = 0.4345, P < 0.05).
Group n - + ++ +++ ADH 39 2 8 24 5 Peri-PM with ADH 11 0 2 2 7 Total 50 2 10 26 12 ADH, atypical ductal hyperplasia; Peri-PM with ADH, peripheral papilloma with atypical ductal hyperplasia. Significant differences existed between the 2 tissue types (z = -2.4691, P < 0.05).
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