Skip to main content

Main menu

  • Home
  • About
    • About CBM
    • Editorial Board
    • Announcement
  • Articles
    • Ahead of print
    • Current Issue
    • Archive
    • Collections
    • Cover Story
  • For Authors
    • Instructions for Authors
    • Resources
    • Submit a Manuscript
  • For Reviewers
    • Become a Reviewer
    • Instructions for Reviewers
    • Resources
    • Outstanding Reviewer
  • Subscription
  • Alerts
    • Email Alerts
    • RSS Feeds
    • Table of Contents
  • Contact us
  • Other Publications
    • cbm

User menu

  • My alerts

Search

  • Advanced search
Cancer Biology & Medicine
  • Other Publications
    • cbm
  • My alerts
Cancer Biology & Medicine

Advanced Search

 

  • Home
  • About
    • About CBM
    • Editorial Board
    • Announcement
  • Articles
    • Ahead of print
    • Current Issue
    • Archive
    • Collections
    • Cover Story
  • For Authors
    • Instructions for Authors
    • Resources
    • Submit a Manuscript
  • For Reviewers
    • Become a Reviewer
    • Instructions for Reviewers
    • Resources
    • Outstanding Reviewer
  • Subscription
  • Alerts
    • Email Alerts
    • RSS Feeds
    • Table of Contents
  • Contact us
  • Follow cbm on Twitter
  • Visit cbm on Facebook
Research ArticleResearch Article

Inhibition of Differentiation by Transforming Growth Factor ß1 in Rhabdomyosarcoma Cells

Shouli Wang, Huihua Yao, Zhenghong Qin, Shigang Li, Yizhong Feng, Xiuzhen Wang, Min Deng, Lingling Guo and Lifeng Zhang
Chinese Journal of Clinical Oncology October 2007, 4 (5) 327-332; DOI: https://doi.org/10.1007/s11805-007-0327-x
Shouli Wang
1Molecular Pathology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: wangsoly112{at}hotmail.com
Huihua Yao
2Department of Surgery, the Second Affiliated Hospital of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Zhenghong Qin
3Pharmacology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shigang Li
1Molecular Pathology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yizhong Feng
1Molecular Pathology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiuzhen Wang
1Molecular Pathology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Min Deng
1Molecular Pathology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lingling Guo
1Molecular Pathology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lifeng Zhang
1Molecular Pathology Laboratory, Medical School of Soochow University, Suzhou 215123, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • References
  • PDF
Loading

REFERENCES

  1. ↵
    1. Massague J,
    2. Chen YG.
    Controlling TGF-β signaling. Genes Dev 2000; 14: 627-644.
    OpenUrlFREE Full Text
  2. ↵
    1. Levy L,
    2. Hill CS.
    Alterations in components of the TGF-ß superfamily signaling pathways in human cancer. Cytokine Growth Factor Rev 2006; 17: 41-58.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    1. Sporn MB,
    2. Roberts AB.
    TGF-β: Problems and prospects. Cell Regul 1990; 1: 875-882.
    OpenUrlPubMedWeb of Science
  4. ↵
    1. Liu D,
    2. Black BL,
    3. Derynck R.
    TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes 2001; 22: 2950-2966.
    OpenUrl
  5. ↵
    1. Olson EN.
    Interplay between proliferation and differentiation within the myogenic lineage. Development Biology 1992; 154: 261-272.
    OpenUrl
  6. ↵
    1. Dias P,
    2. Pharham DM,
    3. Shapiro DN, et al.
    Myogenic regulatory protein (MyoD1) expression in childhood solid tumors: Diagnostic utility in rhabdomyosarcoma. Am J Pathol 1991; 137:1283-1291.
    OpenUrl
  7. ↵
    1. Parham DM.
    The molecular biology of childhood rhabdomyosarcoma. Semin Diagn Pathol 1994; 11: 39-46.
    OpenUrlPubMed
  8. ↵
    1. Wang H,
    2. Yang GH,
    3. Bu H, et al.
    Systematic analysis of the TGF-β/Smad signaling pathway in the rhabdomyosarcoma cell line RD. Int J Exp Path 2003; 84:153-163.
    OpenUrlPubMed
  9. ↵
    1. Ye L,
    2. Zhang HY,
    3. Wang H, et al.
    Effects of transforming growth factor beta1 on the growth of rhabdomyosarcoma cell line RD. Chin Med J 2005; 118: 678-686.
    OpenUrl
  10. ↵
    1. McAllister RM,
    2. Melnyk J,
    3. Finkelstein JZ, et al.
    Cultivation in vitro of cells derived from a human rhabdomyosarcoma. Cancer 1969; 24: 520-526.
    OpenUrlCrossRefPubMedWeb of Science
  11. ↵
    1. Jason WB,
    2. Joe CW,
    3. Marieke M, et al.
    Differentiation of rhabdomyosarcoma cell lines using retinoic acid. Pediatr Blood Cancer 2006; 47: 733-784.
    OpenUrl
  12. ↵
    1. Stevens MCG.
    Treatment for childhood rhabdomyosarcoma: the cost of cure. Lancet Oncol 2005; 6: 77-84.
    OpenUrlCrossRefPubMed
  13. ↵
    1. Xu Q,
    2. Wu Z.
    The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells. J Biol Chem 2000; 275: 36750-36757.
    OpenUrlAbstract/FREE Full Text
  14. ↵
    1. Ricaud S,
    2. Vernus B,
    3. Duclos M, et al.
    Inhibition of autocrine secretion of myostatin enhances terminal differentiation in human rhabdomyosarcoma cells. Oncogene 2003; 22: 8221-8232.
    OpenUrlCrossRefPubMedWeb of Science
  15. ↵
    1. Okuno M,
    2. Kojima S,
    3. Matsushima-Nishiwaki R, et al.
    Retinoids in Cancer Chemoprevention Current Cancer Drug Targets 2004; 4: 285-298.
    OpenUrl
  16. ↵
    1. Hamade A,
    2. Deries M,
    3. Begemann G, et al.
    Retinoic acid activates myogenesis in vivo through Fgf8 signalling. Dev Biol 2006; 289:127-140.
    OpenUrlCrossRefPubMed
  17. ↵
    1. Ricaud S,
    2. Vernus B,
    3. Bonnieu A, et al.
    Response of human rhabdomyosarcoma cell lines to retinoic acid: relationship with induction of differentiation and retinoic acid sensitivity. Exp Cell Res 2005; 311:192-204.
    OpenUrlPubMed
  18. ↵
    1. Sebire NJ,
    2. Malone M.
    Myogenin and MyoD1 expression in paediatric rhabdomyosarcomas. J Clin Pathol 2003;56:412-416.
    OpenUrlAbstract/FREE Full Text
  19. ↵
    1. Kumar S,
    2. Perlman E,
    3. Harris CA et al.
    Myogenin is a specific marker for rhabdomyosarcoma: an immunohistochemical study in paraffin-embedded tissue. Mod Pathol 2000;13:988-993.
    OpenUrlCrossRefPubMedWeb of Science
  20. ↵
    1. Myer A,
    2. Olson EN,
    3. Klein WH.
    MyoD cannot compensate for the absence of myogenin during skeletal muscle differentiation in murine embryonic stem cells. Dev Biol 2001; 229:340-350.
    OpenUrlCrossRefPubMedWeb of Science
  21. ↵
    1. Guo H,
    2. Zhang HY,
    3. Wang SL, et al.
    Smad4 and ERK2 stimulated by transforming growth factor beta1 in rhabdomyosarcoma. Chin Med J 2007; 120: 515-521.
    OpenUrl
PreviousNext
Back to top

In this issue

Cancer Biology and Medicine: 4 (5)
Chinese Journal of Clinical Oncology
Vol. 4, Issue 5
October 2007
  • Table of Contents
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Cancer Biology & Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Inhibition of Differentiation by Transforming Growth Factor ß1 in Rhabdomyosarcoma Cells
(Your Name) has sent you a message from Cancer Biology & Medicine
(Your Name) thought you would like to see the Cancer Biology & Medicine web site.
Citation Tools
Inhibition of Differentiation by Transforming Growth Factor ß1 in Rhabdomyosarcoma Cells
Shouli Wang, Huihua Yao, Zhenghong Qin, Shigang Li, Yizhong Feng, Xiuzhen Wang, Min Deng, Lingling Guo, Lifeng Zhang
Chinese Journal of Clinical Oncology Oct 2007, 4 (5) 327-332; DOI: 10.1007/s11805-007-0327-x

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Inhibition of Differentiation by Transforming Growth Factor ß1 in Rhabdomyosarcoma Cells
Shouli Wang, Huihua Yao, Zhenghong Qin, Shigang Li, Yizhong Feng, Xiuzhen Wang, Min Deng, Lingling Guo, Lifeng Zhang
Chinese Journal of Clinical Oncology Oct 2007, 4 (5) 327-332; DOI: 10.1007/s11805-007-0327-x
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • INTRODUCTION
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Intussusception Induced by Transverse Colon Lipoma in a Young Male Patient—One Case Report
  • Changing Paradigms in Clinical Oncology Research — Highlights from the 2011 ASCO Annual Meeting and Beyond
  • B7-H4 Expression and Increased Death Risk of Cancer Patients: A Meta-Analysis
Show more Research Article

Similar Articles

Keywords

  • TGF-ß1
  • proliferation
  • differentiation
  • rhabdomyosarcoma

Navigate

  • Home
  • Current Issue

More Information

  • About CBM
  • About CACA
  • About TMUCIH
  • Editorial Board
  • Subscription

For Authors

  • Instructions for authors
  • Journal Policies
  • Submit a Manuscript

Journal Services

  • Email Alerts
  • Facebook
  • RSS Feeds
  • Twitter

 

© 2026 Cancer Biology & Medicine

Powered by HighWire